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ANAGRELIDE IMPURITY 5

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ANAGRELIDE IMPURITY 5 Basic information

Product Name:
ANAGRELIDE IMPURITY 5
Synonyms:
  • 5,6-Dichloro-1,4-dihydro-2-quinazolinamine
  • 2-AMino-5,6-dichloro-3,4-dihydroquinazoline
  • ANAGRELIDE IMPURITY 5
  • Anagrelide Impurity 24
  • 2-Quinazolinamine, 5,6-dichloro-1,4-dihydro-
  • 5,6-dichloro-3,4-dihydroquinazolin-2-amine
  • Anagrelide Impurity 27
  • AgrelideImpurity3-13C6
CAS:
444904-63-6
MF:
C8H7Cl2N3
MW:
216.07
Mol File:
444904-63-6.mol
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ANAGRELIDE IMPURITY 5 Chemical Properties

Melting point:
205 - 208oC
Boiling point:
357.5±52.0 °C(Predicted)
Density 
1.67±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
8.41±0.20(Predicted)
color 
Light Yellow to Yellow
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ANAGRELIDE IMPURITY 5 Usage And Synthesis

Uses

2-Amino-5,6-dichloro-3,4-dihydroquinazoline is a metabolite of Anagrelide (A637300), a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic.

Definition

ChEBI: 2-Amino-5,6-dichloro-3,4,-dihydroquinazoline is a member of quinazolines.

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