Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester Basic information
- Product Name:
- Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
- Synonyms:
-
- Pal-Glu(OSu)-OtBu
- 1-tert-butyl 2,5-dioxopyrrolidin-1-yl (2S)-2-hexadecanaMidopentanedioate
- Nε-Hexadecanoyl-L-glutaMic Acid α-t-Butyl-γ-2,5-dioxopyrrolidin-1-yl-diester
- Nε-Palmitoyl-L-glutamic Acid
- N-Palmitoyl-L-glutamic acid α-tert- butyl ester γ-succinimidyl ester≥ 99% (HPLC)
- Palmitoyl-Glu(OSu)-OtBu
- Palm-L-Glu(OSu)-OtBu
- Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester
- CAS:
- 204521-63-1
- MF:
- C29H50N2O7
- MW:
- 538.72
- Product Categories:
-
- Amino Acids & Derivatives
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 204521-63-1.mol
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Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester Chemical Properties
- Melting point:
- 86.0 to 90.0 °C
- Density
- 1.08±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 14.40±0.46(Predicted)
- color
- White to Pale Yellow
- Stability:
- Sensitive to light, heat and humidity
- CAS DataBase Reference
- 204521-63-1
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Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester Usage And Synthesis
Description
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester is a PEG ligand, a synthetic side chain of liraglutide, a peptide drug used in the treatment of type 2 diabetes. It can also be used to prepare Glp-2 derivatives modified with lipophilic substituents.
Chemical Properties
White crystalline powder
Uses
Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. An antiobesity agent.
Uses
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl Ester is used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles.
Nε-PalMitoyl-L-glutaMic Acid γ-SucciniMidyl-α-tert-butyl EsterSupplier
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