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N-ACETYLLACTOSAMINE

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N-ACETYLLACTOSAMINE Basic information

Product Name:
N-ACETYLLACTOSAMINE
Synonyms:
  • Glucopyranose Galf1-b-4-GlcNAc
  • 2-Acetamido-2-deoxy-4-O-D-galactopyranosyl-D-glucopyranose, N-Acetyl-4-O-(D-galactopyranosyl)-D-glucosamine
  • 2-Acetamido-2-deoxy-4-O--D-galactopyranosyl-D-glucopyranose
  • Gal-(1-4)-D-GlcNAc
  • 2-Acetylamino-4-O-β-D-galactopyranosyl-2-deoxy-D-glucopyranose
  • 4-O-(β-D-Galactopyranosyl)-2-(acetylamino)-2-deoxy-D-glucopyranose
  • 4-O-(β-D-Galactopyranosyl)-2-acetylamino-2-deoxy-D-glucopyranose
  • 4-O-β-D-Galactopyranosyl-2-(acetylamino)-2-deoxy-D-glucopyranose
CAS:
32181-59-2
MF:
C14H25NO11
MW:
383.35
Product Categories:
  • Oligosaccharides
  • Carbohydrates
Mol File:
32181-59-2.mol
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N-ACETYLLACTOSAMINE Chemical Properties

Melting point:
191-192
Boiling point:
858.1±65.0 °C(Predicted)
Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: 10 mg/mL, clear, colorless
pka
12.85±0.20(Predicted)
form 
Solid
color 
White to Pale Beige
BRN 
96808
Stability:
Hygroscopic
LogP
-4.456 (est)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37
WGK Germany 
3
3-10
Hazard Note 
Irritant
HS Code 
29400090

MSDS

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N-ACETYLLACTOSAMINE Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

A component of oligosaccharide portion of many N- and O-linked glycoproteins. It is a building unit for the antigenic determinants of a number of certain human blood group activities as well as of the ABH Type 2 determinants

Uses

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

Uses

N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.

Definition

ChEBI: Beta-D-Galp-(1->4)-D-GlcpNAc is a disaccharide consisting of beta-D-galactose linked via a (1->4)-glycosidic bond to N-acetyl-D-glucosamine. It is a glucosamine oligosaccharide and a member of lactosamines.

Purification Methods

Purify N-acetyl-D-lactosamine by recrystallisation from MeOH (with 1 mol of MeOH) or from H2O. It is available commercially as a solution of 0.5g/mL of H2O. [Zilliken J Biol Chem 271 181 1955, Beilstein 17 IV 3452.]

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