N-ACETYLLACTOSAMINE
N-ACETYLLACTOSAMINE Basic information
- Product Name:
- N-ACETYLLACTOSAMINE
- Synonyms:
-
- Glucopyranose Galf1-b-4-GlcNAc
- 2-Acetamido-2-deoxy-4-O-D-galactopyranosyl-D-glucopyranose, N-Acetyl-4-O-(D-galactopyranosyl)-D-glucosamine
- 2-Acetamido-2-deoxy-4-O--D-galactopyranosyl-D-glucopyranose
- Gal-(1-4)-D-GlcNAc
- 2-Acetylamino-4-O-β-D-galactopyranosyl-2-deoxy-D-glucopyranose
- 4-O-(β-D-Galactopyranosyl)-2-(acetylamino)-2-deoxy-D-glucopyranose
- 4-O-(β-D-Galactopyranosyl)-2-acetylamino-2-deoxy-D-glucopyranose
- 4-O-β-D-Galactopyranosyl-2-(acetylamino)-2-deoxy-D-glucopyranose
- CAS:
- 32181-59-2
- MF:
- C14H25NO11
- MW:
- 383.35
- EINECS:
- 246-914-5
- Product Categories:
-
- Oligosaccharides
- Carbohydrates
- Mol File:
- 32181-59-2.mol
N-ACETYLLACTOSAMINE Chemical Properties
- Melting point:
- 191-192
- Boiling point:
- 858.1±65.0 °C(Predicted)
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: 10 mg/mL, clear, colorless
- pka
- 12.85±0.20(Predicted)
- form
- Solid
- color
- White to Pale Beige
- optical activity
- +28
- Water Solubility
- water: 5mg/mL
- BRN
- 96808
- Stability:
- Hygroscopic
- LogP
- -4.456 (est)
MSDS
- Language:English Provider:SigmaAldrich
N-ACETYLLACTOSAMINE Usage And Synthesis
Chemical Properties
White Crystalline Solid
Uses
A component of oligosaccharide portion of many N- and O-linked glycoproteins. It is a building unit for the antigenic determinants of a number of certain human blood group activities as well as of the ABH Type 2 determinants
Uses
N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Uses
N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.
Definition
ChEBI: Beta-D-Galp-(1->4)-D-GlcpNAc is a disaccharide consisting of beta-D-galactose linked via a (1->4)-glycosidic bond to N-acetyl-D-glucosamine. It is a glucosamine oligosaccharide and a member of lactosamines.
Purification Methods
Purify N-acetyl-D-lactosamine by recrystallisation from MeOH (with 1 mol of MeOH) or from H2O. It is available commercially as a solution of 0.5g/mL of H2O. [Zilliken J Biol Chem 271 181 1955, Beilstein 17 IV 3452.]
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N-ACETYLLACTOSAMINE(32181-59-2)Related Product Information
- N-ACETYLLACTOSAMINE
- ALPHA-NEU5AC-[2->6]-BETA-GAL-[1->4]-BETA-GLCNAC-[1->3]-BETA-GAL-[1->4]-GLC SODIUM SALT
- N-ACETYLLACTOSAMINE HEPTAACETATE 98,N-Acetyllactosamine heptaacetate 98%
- 2-Deoxy-D-glucose
- 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-D-GLUCOPYRANOSE
- N-Acetyl-D-Glucosamine
- Lewis X Trisaccharide, Methyl Glycoside
- SialylLewisXmethylglycoside
- DIFUCOSYLLACTO-N-HEXAOSE (A)
- 2-PHTHALIMIDOLACTOSAMINE, HEPTAACETATE
- LewisYtetrasaccharide
- FUCOSYLLACTO-N-HEXAOSE III FROM HUMAN
- BETA-D-GAL-[1->4]-BETA-D-GLCNAC-1->O-CETE
- LACTO-N-FUCOPENTAOSE III
- TFLNH[A]
- LACTO-N-NEOTETRAOSE
- 3'-N-ACETYLNEURAMINYL-N-ACETYLLACTOSAMINE SODIUM SALT
- LEWIS X TRISACCHARIDE