Adelmidrol Chemical Properties

Melting point:

132-134℃

Boiling point:

596.4±45.0 °C(Predicted)

Density 

1.097±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO:77.5(Max Conc. mg/mL);282.47(Max Conc. mM)
Ethanol:28.0(Max Conc. mg/mL);102.06(Max Conc. mM)
Water:55.0(Max Conc. mg/mL);200.47(Max Conc. mM)

pka

14.19±0.10(Predicted)

form 

Solid

color 

White to off-white

InChI

InChI=1S/C13H26N2O4/c16-10-8-14-12(18)6-4-2-1-3-5-7-13(19)15-9-11-17/h16-17H,1-11H2,(H,14,18)(H,15,19)

InChIKey

PAHZPHDAJQIETD-UHFFFAOYSA-N

SMILES

C(NCCO)(=O)CCCCCCCC(NCCO)=O

Adelmidrol Usage And Synthesis

Description

N,N'-Bis(2-hydroxyethyl)nonanediamide, also named Admidol, is an anti-inflammatory ethanolamide derivative. It is hydrophilic and hydrophobic, favoring its solubility in water and organic media. As an naturally occurring saturated dicarboxylic acid, it is found in trace amounts in the human body and in some whole grains. Adelmidrol is an analogue of palmitoylethanolamide (PEA), which is a well-known anti-inflammatory and anti-oxidant compound.  Adelmidrol  was able to manage the significant incapacity of antioxidants and elevation of the oxidant burden[1-2].

Uses

Adelmidrol is an anti-inflammatory. It can be used in biological study of protective effect of adelmidrol as new palmitoylethanolamide analog for pharmacol. treatment of inflammatory bowel disease in mouse model.

Biological Activity

Adelmidrol is an analog of hexadecylamide ethanol (PEA) with anti-inflammatory activity.

in vitro

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