20-(tert-Butoxy)-20-oxoicosanoic acid Chemical Properties

Boiling point:

496.0±18.0 °C(Predicted)

Density 

0.942±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

form 

Solid

pka

4.78±0.10(Predicted)

color 

White to off-white

InChI

InChI=1S/C24H46O4/c1-24(2,3)28-23(27)21-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-22(25)26/h4-21H2,1-3H3,(H,25,26)

InChIKey

JUCDAUSILDWYOA-UHFFFAOYSA-N

SMILES

C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCCCC(O)=O

CAS DataBase Reference

683239-16-9

Safety Information

HS Code 

2918199890

20-(tert-Butoxy)-20-oxoicosanoic acid Usage And Synthesis

Description

20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and in the synthesis of PROTACs.

Chemical Properties

Eicosanedioic acid mono-tert-butyl ester is a solid at room temperature and pressure, with poor solubility in water but some solubility in alcohol organic solvents. It has certain acidity, and the carboxyl unit at one end of the alkyl chain in its structure can be esterified with alcohol compounds under the action of acid catalyst to obtain the corresponding diester derivatives.

Uses

20-(tert-Butoxy)-20-oxoicosanoic acid is a useful research chemical compound.

IC 50

Non-cleavable Linker

20-(tert-Butoxy)-20-oxoicosanoic acid(683239-16-9)Related Product Information

• Butyl benzoate
• Butyl acetate
• EICOSANEDIOIC ACID
• OCTADECANEDIOIC ACID MONO-TERT-BUTYL ESTER
• 16-(tert-Butoxy)-16-oxopalmitic acid, tert-Butyl 15-carboxypentadecanoate
• BEHENIC ACID
• HEXADECANEDIOIC ACID
• NONADECANEDIOIC ACID
• HEPTADECANEDIOIC ACID
• MONOBUTYL PHTHALATE