CID 16020046 Chemical Properties

Boiling point:

748.1±60.0 °C(Predicted)

Density 

1.425±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: soluble1mg/mL, clear (warmed)

pka

4.27±0.10(Predicted)

form 

powder

color 

white to beige

InChI

InChI=1S/C25H19N3O4/c1-14-5-7-15(8-6-14)21-20-22(27-26-21)24(30)28(18-11-9-16(10-12-18)25(31)32)23(20)17-3-2-4-19(29)13-17/h2-13,23,29H,1H3,(H,26,27)(H,31,32)

InChIKey

VGUQVYZXABOXCX-UHFFFAOYSA-N

SMILES

C(O)(=O)C1=CC=C(N2C(C3=CC=CC(O)=C3)C3C(C4=CC=C(C)C=C4)=NNC=3C2=O)C=C1

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/38

Safety Statements 

26

WGK Germany 

3

Storage Class

11 - Combustible Solids

CID 16020046 Usage And Synthesis

Uses

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Uses

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Biochem/physiol Actions

CID16020046 is a potent and a selective GPR55 antagonist that inhibits GPR55-mediated ERK1/2 phosphorylation. CID16020046 inhibits LPI-induced Ca2+ signaling in HEK-GPR55 cells.

storage

Store at +4°C

CID 16020046(834903-43-4)Related Product Information

• Uracil
• Dihydroxybenzoic acid
• Diphenylphosphine oxide