DFSX-2 Chemical Properties

Melting point:

201-209 °C(Solv: water (7732-18-5))

Boiling point:

652.5±55.0 °C(Predicted)

Density 

1.47±0.1 g/cm3(Predicted)

storage temp. 

Store at -20 °C

solubility 

DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml

pka

0.92±0.10(Predicted)

Appearance

Off-White Solid

InChIKey

VMXLACIKUJJQTC-UHFFFAOYSA-N

SMILES

N1(C2=NC(N)=C(F)C=C2F)C2=C(C=C(F)C(N3CC(OC(=O)C(C)C)C3)=C2)C(=O)C(C(OCC)=O)=C1

DFSX-2 Usage And Synthesis

Description

DFSX-2 is a precursor in the synthesis of the fluoroquinolone antibiotic ABT-492 (delafloxacin; Item Nos. 20314 | 27935).1WARNING This product is not for human or veterinary use.

References

[1] ANTHONY R. HAIGHT. Synthesis of the Quinolone ABT-492: Crystallizations for Optimal Processing[J]. Organic Process Research & Development, 2006, 10 4: 751-756. DOI: 10.1021/op060054e

DFSX-2(442526-91-2)Related Product Information

• NA
• Delafloxacin Impurity 8
• Deschloro Delafloxacin Ethyl Ester
• Delafloxacin Dimer Impurity 1
• Benzenepropanoic acid, α-[[(6-amino-3,5-difluoro-2-pyridinyl)amino]methylene]-3-chloro-2,4,5-trifluoro-β-oxo-, ethyl ester
• NA
• Delafloxacin Ethyl Ester
• 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester
• NA
• NA
• Delafloxacin Impurity 7
• Deschloro Delafloxacin
• NA
• 3-quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-
• Atracurium Iodide (Mixture of Diastereomers)
• 5-Aza-2'-deoxycytidine
• Levofloxacin
• Ciprofloxacin hydrochloride