(2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE
(2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE Basic information
- Product Name:
- (2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE
- Synonyms:
-
- (2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE
- (2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDINE-2-YL)-METHYL]-PYRROLIDINE
- (-)-2-HYDROXYMETHYL-(1-METHYLPYRROLIDIN- 2-YLME)PYRROLIDINE
- 2-hydroxymethyl-(1-methylpyrrolidin-2ylmethyl)pyrrolidine
- (2S,2S)-1-(1-Methyl-2-pyrrolidinylmethyl)pyrrolidine-2-methanol
- (2S,2''S)-(-)-2-HYDROXYMETHYL-1-[(1-METHY
- 2-PyrrolidineMethanol,1-[[(2S)-1-Methyl-2-pyrrolidinyl]Methyl]-, (2S)-
- (1-((1-Methylpyrrolidin-2-yl)methyl)pyrrolidin-2-yl)methanol
- CAS:
- 66283-23-6
- MF:
- C11H22N2O
- MW:
- 198.31
- Mol File:
- 66283-23-6.mol
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(2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE Chemical Properties
- Boiling point:
- 275-277 °C
- alpha
- [α]28D -130° (c 0.36, EtOH)
- refractive index
- n20/D 1.494
- solubility
- sol hexane, toluene, Me2O, Et2O, n-Pr2O, THF, dimethoxymethane.
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Safety Information
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- 1760
- HazardClass
- 8
- PackingGroup
- III
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(2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE Usage And Synthesis
Uses
(2S,2′S)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine is a chiral ligand for alkyllithium, dialkylmagnesium, alkynyllithium, and functionalized organolithiums in the enantioselective addition to aldehydes; accelerates the basicity of alkyllithiums; catalyzes the addition of dialkylzinc to aldehyde.
Preparation
Preparative Method of (2S,2′S)-2-Hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine: reduction of N-[N(-benzyloxycarbonyl)prolyl]proline methyl ester with Lithium Aluminum Hydride affords the title reagent in 81% yield.
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(2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE(66283-23-6)Related Product Information
- BPP 9A
- Fmoc-Pro-Pro-OH
- (2S,2'S)-(-)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)-METHYL]-PYRROLIDINE
- BOC-PRO-PRO-OH
- H-PRO-PRO-PRO-OH
- Z-PRO-PRO-OH
- BRADYKININ POTENTIATOR B
- BIG ENDOTHELIN-2 (22-37), HUMAN
- GLY-PRO-HYDROXY-PRO ACETATE SALT
- H-GLY-PRO-HYP-OH
- FMOC-GLY-PRO-HYP-OH
- HIV (GP120) FRAGMENT (421-438)
- H-GLY-PRO-PRO-OH
- BOC-PRO-PRO-PRO-PRO-OH
- BRADYKININ POTENTIATOR C
- DOLASTATIN 15
- H-PRO-PRO-PRO-PRO-OH
- H-ARG-PRO-PRO-OH SULFATE SALT