Naringenin-7-O-glucuronide
Naringenin-7-O-glucuronide Basic information
- Product Name:
- Naringenin-7-O-glucuronide
- Synonyms:
-
- β-D-Glucopyranosiduronic acid, 3,4-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-2H-1-benzopyran-7-yl
- β-D-Glucopyranosiduronic acid, 3,4-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-2H-1-benzopyran-7-yl
- CAS:
- 1237479-07-0
- MF:
- C21H20O11
- MW:
- 448.38
- Mol File:
- 1237479-07-0.mol
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Naringenin-7-O-glucuronide Chemical Properties
- solubility
- DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 2 mg/ml
- form
- A crystalline solid
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Naringenin-7-O-glucuronide Usage And Synthesis
Description
Naringenin-7-O-β-D-glucuronide is a metabolite of the flavonoid naringenin .1 It is formed from naringenin primarily by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1, UGT1A3, UGT1A6, and UGT1A9.2
References
1. Pereira-Caro, G., Borges, G., van der Hooft, J., et al. Orange juice (poly)phenols are highly bioavailable in humans Am. J. Clin. Nutr. 100(5),1378-1384(2014).
2. Robotham, S.A., and Brodbelt, J.S. Identification of flavone glucuronide isomers by metal complexation and tandem mass spectrometry: Regioselectivity of uridine 5'-