ANTI-CHD3 Chemical Properties

storage temp. 

-20°C

form 

liquid

biological source

rabbit

Safety Information

WGK Germany 

WGK 1

Storage Class

12 - Non Combustible Liquids

ANTI-CHD3 Usage And Synthesis

Uses

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]