8-BENZYLTHIOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
8-BENZYLTHIOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information
- Product Name:
- 8-BENZYLTHIOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Synonyms:
-
- 8-benzylthioadenosine-3’,5’-cyclicmonophosphate(8-bt-camp),sodiumsalt
- 8-BT-CAMP SODIUM SALT
- 8-BENZYLTHIOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 8-BT-cAMP
- CAS:
- 50655-17-9
- MF:
- C17H17N5NaO6PS
- MW:
- 473.38
- Mol File:
- 50655-17-9.mol
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8-BENZYLTHIOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis
Uses
8-Benzylthio-cAMP is a derivative of cyclic adenosine monophosphate (cAMP). 8-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinases. Compared with cyclic adenosine monophosphate, it is more stable to phosphodiesterase (PDE) hydrolysis and has higher membrane permeability. 8-Bn-cAMP can be used to study the role of cAMP in regulating cell proliferation, differentiation and apoptosis[1].
References
[1] KATAOKA S, et al. Studies on the Synthesis of Compounds Related to Adenosine 3', 5'-Cyclic Phosphate. V.: Synthesis and Cardiac Effect of N6-Alkyladenosine 3', 5'-Cyclic Phosphates and Their 8-Benzylthio Derivatives[J]. Chemical and pharmaceutical bulletin, 1988, 36(6): 2212-2219. DOI:10.1248/cpb.36.2212
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