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Adenosine 3',5'-cyclic monophosphate sodium salt

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Adenosine 3',5'-cyclic monophosphate sodium salt Basic information

Product Name:
Adenosine 3',5'-cyclic monophosphate sodium salt
Synonyms:
  • ADENOSINE-3',5'-CYCLIC PHOSPHATE SODIUM
  • ADENOSINE-3',5'-MONOPHOSPHORIC ACID SODIUM SALT
  • ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM
  • ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE MONOSODIUM SALT
  • ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • A-3:5-MP, SODIUM SALT
  • 3',5'-CYCLIC AMP NA
CAS:
37839-81-9
MF:
C10H13N5NaO6P
MW:
353.21
EINECS:
253-328-3
Product Categories:
  • Biochemistry
  • Nucleosides, Nucleotides & Related Reagents
  • Nucleotides and their analogs
  • API
  • Nucleoside Mono
Mol File:
37839-81-9.mol
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Adenosine 3',5'-cyclic monophosphate sodium salt Chemical Properties

storage temp. 
-20°C
solubility 
H2O: 50 mg/mL
form 
powder
color 
white
Water Solubility 
Soluble in water (50 mg/ml).
BRN 
54612
Stability:
Hygroscopic
CAS DataBase Reference
37839-81-9
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
2
RTECS 
AU7357900
10-21
HS Code 
29349990

MSDS

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Adenosine 3',5'-cyclic monophosphate sodium salt Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

Adenosine 3?,5?-cyclic monophosphate sodium salt monohydrate is used as an activator of protein kinase A (PKA) . A key regulator of many cellular reactions. Released in response to hormonal stimulation. . Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.

Uses

Adenosine 3',5'-cyclic monophosphate sodium salt is an Adenosine (A280400) derivative useful as anticancer agent.

Biochem/physiol Actions

Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.

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