ADENOSINE5'-MONOPHOSPHATESODIUMSALT Chemical Properties

storage temp. 

Storage temp. 2-8°C

form 

Liquid

color 

Colorless to light yellow

LogP

-0.22

Safety Information

RTECS 

AU7481600

ADENOSINE5'-MONOPHOSPHATESODIUMSALT Usage And Synthesis

Uses

Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.

As a flavor ingredient

Identification

Uses

Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].

References

[1] Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287(8):5301-9. DOI:10.1074/jbc.M111.291666
[2] Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985. DOI:10.1038/cddis.2013.516
[3] Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3(3):161-74. DOI:10.1016/0166-3542(83)90023-2

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