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Adenosine-5'-diphosphate disodium salt

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Adenosine-5'-diphosphate disodium salt Basic information

Product Name:
Adenosine-5'-diphosphate disodium salt
Synonyms:
  • 5'-ADP-NA2
  • adenosine5’-(trihydrogendiphosphate),disodiumsalt
  • Adenosine-5'-diphosphata(ADP),disodium salt
  • Adenosine-5'-diphosphate disodiuM salt(ADPNa)
  • Adenosine 5 -Diphosphate DisodiuM Salt 
  • 5'-ADENYLDIPHOSPHORIC ACID, DISODIUM SALT
  • ADENOSINE DIPHOSPHATE DINA SALT
  • ADP DISODIUM
CAS:
16178-48-6
MF:
C10H15N5O10P2.2Na
MW:
471.16
EINECS:
240-314-7
Product Categories:
  • Pharmaceutical Intermediates
  • Biochemistry
  • Nucleosides, Nucleotides & Related Reagents
  • Nucleotides and their analogs
  • Nucleic acids
  • nucleoside
  • Pharmaceutical
Mol File:
16178-48-6.mol
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Adenosine-5'-diphosphate disodium salt Chemical Properties

storage temp. 
-20°C
form 
Powder
color 
White
optical activity
[α]20/D 29.6±1°, c = 0.5% in 0.5 M Na2HPO4
Water Solubility 
Soluble in water.
Sensitive 
Hygroscopic
BRN 
3645656
InChIKey
AIZARHCNBKWDRW-KWIZKVQNSA-L
SMILES
[Na+].[Na+].C(OP(=O)(O)OP(O)(O)=O)[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H]([O-])[C@@H]1[O-]
CAS DataBase Reference
16178-48-6(CAS DataBase Reference)
EPA Substance Registry System
Adenosine 5'-(trihydrogen diphosphate), disodium salt (16178-48-6)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
10-21
TSCA 
Yes
HS Code 
29349990

MSDS

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Adenosine-5'-diphosphate disodium salt Usage And Synthesis

Description

Adenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.

Chemical Properties

White crystalline powder

Uses

Adenosine-5'-diphosphate disodium salt is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

Application

Adenosine-5'-diphosphate disodium salt is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels.

Biochem/physiol Actions

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y1 and P2Y12. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

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