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Nucleotides and their analogs

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The nucleotide is composed by bases, pentose and phosphoric acid, which is the basic unit of biological macromolecules of nucleic acids. Depending on the difference of pentose in nucleotides, they can be divided into ribonucleotides and deoxyribonucleotides, thus constituting two kinds of nucleic acid: ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). The bases composing nucleotide have two types of pyrimidine and purine. Pyrimidine is a 6 ring heterocyclic compound containiong 2 nitrogen atoms, and the common pyrimidine bases in nucleotide include cytosine nucleotides(C), uracil(V)and thymine(T). Purine is a heterocyclic compound containing four nitrogen. Adenine(A) and guanine(G) are the major purine nucleotide base composed nucleotide. Nucleotide is formed by the esterification of sugar hydroxyl groups in nucleoside with phosphated acid after the formation of nucleoside via the condensation of ribose or deoxyribose with bases. The free 5 'nucleotide present in organisms is formed by the esterification of hydroxyl groups of the C5 with pentose phosphate.

Nucleotide is a colorless crystalline powder, which is soluble in water and insoluble in organic solvents. And its solution have optically active, and has a strong UV absorption at 260nm. It is an amphoteric electrolyte, which have different dissociation situations at different pH. These nature has great practical value in the preparation, analysis and measurement of nucleotide.

The application of nucleotide substances is very broad, such as ATP, GTP, 5'- nucleotides, etc. can be used as a supplementary drug; 5'-fluorouracil nucleotide analogs have the anti-cancer effect; poly-cytidine acid is the inducer of interferon and has antiviral activity; in the food industry , inosinic acid and guanylic acid are the co-fresheners of aginomoto, which can greatly increase the flavor of aginomoto; in biological research, nucleotide materials are also the essential reagents.

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Structure:
Chemical Name:
ADP
CAS:
58-64-0
MF:
C10H15N5O10P2
Structure:
Chemical Name:
Thymidine
CAS:
50-89-5
MF:
C10H14N2O5
Structure:
Chemical Name:
5-Chlorouracil
CAS:
1820-81-1
MF:
C4H3ClN2O2
Structure:
Chemical Name:
Guanosine 5'-monophosphate disodium salt
CAS:
5550-12-9
MF:
C10H12N5Na2O8P
Structure:
Chemical Name:
Mesitylene-2-sulfonyl chloride
CAS:
773-64-8
MF:
C9H11ClO2S
Structure:
Chemical Name:
Adenine sulphate
CAS:
321-30-2
MF:
C10H12N10O4S
Structure:
Chemical Name:
6-Mercaptopurine monohydrate
CAS:
6112-76-1
MF:
C5H6N4OS
Structure:
Chemical Name:
6-Chloropurine riboside
CAS:
2004-06-0
MF:
C10H11ClN4O4
Structure:
Chemical Name:
Cytidine
CAS:
65-46-3
MF:
C9H13N3O5
Structure:
Chemical Name:
5-Fluorouracil
CAS:
51-21-8
MF:
C4H3FN2O2
Structure:
Chemical Name:
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
CAS:
3680-69-1
MF:
C6H4ClN3
Structure:
Chemical Name:
2-Fluoroadenine
CAS:
700-49-2
MF:
C5H4FN5
Structure:
Chemical Name:
2,6-Dihydroxypurine
CAS:
69-89-6
MF:
C5H4N4O2
Structure:
Chemical Name:
Adenosine-5'-diphosphate disodium salt
CAS:
16178-48-6
MF:
C10H13N5Na2O10P2
Structure:
Chemical Name:
Benzoic anhydride
CAS:
93-97-0
MF:
C14H10O3
Structure:
Chemical Name:
5-Nitrouracil
CAS:
611-08-5
MF:
C4H3N3O4
Structure:
Chemical Name:
2,6-Diaminopurine
CAS:
1904-98-9
MF:
C5H6N6
Structure:
Chemical Name:
2,6-Dichloropurine
CAS:
5451-40-1
MF:
C5H2Cl2N4
Structure:
Chemical Name:
5-CARBETHOXYURACIL
CAS:
28485-17-8
MF:
C7H8N2O4
Structure:
Chemical Name:
6-Chloropurine
CAS:
87-42-3
MF:
C5H3ClN4
Structure:
Chemical Name:
6-(Methylthio)purine
CAS:
50-66-8
MF:
C6H6N4S
Structure:
Chemical Name:
DIBENZYL DIISOPROPYLPHOSPHORAMIDITE
CAS:
108549-23-1
MF:
C20H28NO2P
Structure:
Chemical Name:
ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT
CAS:
149022-20-8
MF:
C10H12N5Na2O7P
Structure:
Chemical Name:
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
CAS:
666816-98-4
MF:
C10H9BrN4O2
Structure:
Chemical Name:
5-Nitroso-2,4,6-triaminopyrimidine
CAS:
1006-23-1
MF:
C4H6N6O
Structure:
Chemical Name:
1,2,4-Triazole
CAS:
288-88-0
MF:
C2H3N3
Structure:
Chemical Name:
4,6-Dihydroxy-2-methylpyrimidine
CAS:
40497-30-1
MF:
C5H6N2O2
Structure:
Chemical Name:
Cytidylic acid
CAS:
63-37-6
MF:
C9H14N3O8P
Structure:
Chemical Name:
Guanosine
CAS:
118-00-3
MF:
C10H13N5O5
Structure:
Chemical Name:
5-Ethyluracil
CAS:
4212-49-1
MF:
C6H8N2O2
Structure:
Chemical Name:
2'-Deoxyguanosine monohydrate
CAS:
961-07-9
MF:
C10H15N5O5
Structure:
Chemical Name:
1,2,3-1H-Triazole
CAS:
288-36-8
MF:
C2H3N3
Structure:
Chemical Name:
4-Amino-3-hydrazino-1,2,4-triazol-5-thiol
CAS:
1750-12-5
MF:
C2H6N6S
Structure:
Chemical Name:
2,4-Dihydroxypyrimidine-5-carboxylic acid
CAS:
23945-44-0
MF:
C5H4N2O4
Structure:
Chemical Name:
2'-Deoxyuridine
CAS:
951-78-0
MF:
C9H12N2O5
Structure:
Chemical Name:
N4-Benzoylcytosine
CAS:
26661-13-2
MF:
C11H9N3O2
Structure:
Chemical Name:
Adenosine 5'-triphosphate disodium salt
CAS:
51963-61-2
MF:
C10H14N5Na2O13P3
Structure:
Chemical Name:
Tetrazole
CAS:
288-94-8
MF:
CH2N4
Structure:
Chemical Name:
CYTIDINE 5'-DIPHOSPHOCHOLINE
CAS:
987-78-0
MF:
C14H26N4O11P2
Structure:
Chemical Name:
5-Azacytidine
CAS:
320-67-2
MF:
C8H12N4O5
Structure:
Chemical Name:
N4-Acetylcytosine
CAS:
14631-20-0
MF:
C6H7N3O2
Structure:
Chemical Name:
5-Iodo-2,4-dimethoxypyrimidine
CAS:
52522-99-3
MF:
C6H7IN2O2
Structure:
Chemical Name:
CTP
CAS:
65-47-4
MF:
C9H16N3O14P3
Structure:
Chemical Name:
2,6-Dihydroxy-3-methylpurine
CAS:
1076-22-8
MF:
C6H6N4O2
Structure:
Chemical Name:
Guanine hydrochloride
CAS:
635-39-2
MF:
C5H6ClN5O
Structure:
Chemical Name:
2'-Deoxyinosine
CAS:
890-38-0
MF:
C10H12N4O4
Structure:
Chemical Name:
Purine
CAS:
120-73-0
MF:
C5H4N4
Structure:
Chemical Name:
N-Benzoylaminopurine
CAS:
4005-49-6
MF:
C12H9N5O
Structure:
Chemical Name:
Adenosine 5'-monophosphate disodium salt
CAS:
4578-31-8
MF:
C10H12N5Na2O7P
Structure:
Chemical Name:
6-Hydrazinopurine
CAS:
5404-86-4
MF:
C5H6N6
Structure:
Chemical Name:
Isocytosine
CAS:
108-53-2
MF:
C4H5N3O
Structure:
Chemical Name:
5-Amino-4,6-dichloro-2-methylpyrimidine
CAS:
39906-04-2
MF:
C5H5Cl2N3
Structure:
Chemical Name:
URIC ACID
CAS:
69-93-2
MF:
C5H4N4O3
Structure:
Chemical Name:
5'-O-Dimethoxytrityl-deoxythymidine
CAS:
40615-39-2
MF:
C31H32N2O7
Structure:
Chemical Name:
6-Methoxyguanine
CAS:
20535-83-5
MF:
C6H7N5O
Structure:
Chemical Name:
5-IODO-1,3-DIMETHYLURACIL
CAS:
40738-83-8
MF:
C6H7IN2O2
Structure:
Chemical Name:
4,5,6-TRIAMINOPYRIMIDINE SULFATE
CAS:
6640-23-9
MF:
C4H11N5O5S
Structure:
Chemical Name:
6-Dimethylaminopurine
CAS:
938-55-6
MF:
C7H9N5
Structure:
Chemical Name:
DIHYDROTHYMINE
CAS:
696-04-8
MF:
C5H8N2O2
Structure:
Chemical Name:
1,3-DIMETHYLURIC ACID
CAS:
944-73-0
MF:
C7H8N4O3
Structure:
Chemical Name:
6-Methylpurine
CAS:
2004-03-7
MF:
C6H6N4
Structure:
Chemical Name:
6-Amino-3,7-dihydro-2H-purin-2-one
CAS:
3373-53-3
MF:
C5H5N5O
Structure:
Chemical Name:
5,6-DIHYDROURACIL
CAS:
504-07-4
MF:
C4H6N2O2
Structure:
Chemical Name:
2-Aminopurine
CAS:
452-06-2
MF:
C5H5N5
Chemical Name:
Nucleoside
Structure:
Chemical Name:
DITHIOURACIL
CAS:
2001-93-6
MF:
C4H4N2S2
Structure:
Chemical Name:
1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine
CAS:
1123-54-2
MF:
C4H4N6
Structure:
Chemical Name:
6-AZATHYMINE
CAS:
932-53-6
MF:
C4H5N3O2
Structure:
Chemical Name:
1-(4-NITROBENZENESULFONYL)-1H-1,2,4-TRIAZOLE
CAS:
57777-84-1
MF:
C8H6N4O4S
Structure:
Chemical Name:
5-N-PROPYLURACIL
CAS:
19030-75-2
MF:
C7H10N2O2
Structure:
Chemical Name:
6-Chloroguanine
CAS:
10310-21-1
MF:
C5H4ClN5
Structure:
Chemical Name:
5-METHYLCYTOSINE HYDROCHLORIDE
CAS:
58366-64-6
MF:
C5H8ClN3O
Structure:
Chemical Name:
Flavin adenine dinucleotide disodium salt
CAS:
84366-81-4
MF:
C27H33N9Na2O16P2
Structure:
Chemical Name:
Ethyl tetrazole-5-carboxylate
CAS:
55408-10-1
MF:
C4H6N4O2
Structure:
Chemical Name:
5-METHYLCYTOSINE
CAS:
554-01-8
MF:
C5H7N3O
Structure:
Chemical Name:
6-Methylthioguanine
CAS:
1198-47-6
MF:
C6H7N5S
Structure:
Chemical Name:
DI-TERT-BUTYLDICHLOROSILANE
CAS:
18395-90-9
MF:
C8H18Cl2Si
Structure:
Chemical Name:
8-AZAGUANINE
CAS:
134-58-7
MF:
C4H4N6O
Structure:
Chemical Name:
6-THIOXANTHINE
CAS:
2002-59-7
MF:
C5H4N4OS
Structure:
Chemical Name:
3-ISOBUTYL-1-METHYLXANTHINE
CAS:
28822-58-4
MF:
C10H14N4O2
Structure:
Chemical Name:
Potassium orotate
CAS:
24598-73-0
MF:
C5H3KN2O4
Structure:
Chemical Name:
2,4,5,6-TETRAMETHYLBENZENEDISULFONYL DICHLORIDE
CAS:
97997-76-7
MF:
C10H12Cl2O4S2
Structure:
Chemical Name:
Nicotinamide-N-oxide
CAS:
1986-81-8
MF:
C6H6N2O2
Structure:
Chemical Name:
GUANINE SULFATE
CAS:
10333-92-3
MF:
C10H12N10O6S
Structure:
Chemical Name:
Diethyl chlorothiophosphate
CAS:
2524-04-1
MF:
C4H10ClO2PS
Structure:
Chemical Name:
8-Bromoguanosine
CAS:
4016-63-1
MF:
C10H12BrN5O5
Structure:
Chemical Name:
6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione
CAS:
6972-27-6
MF:
C6H7ClN2O2
Structure:
Chemical Name:
METHYL PHOSPHORODICHLORIDITE
CAS:
3279-26-3
MF:
CH3Cl2OP
Structure:
Chemical Name:
N-MESITYLENESULFONYLIMIDAZOLE
CAS:
50257-39-1
MF:
C12H14N2O2S
Structure:
Chemical Name:
1,3-BENZODITHIOLYLIUM TETRAFLUOROBORATE
CAS:
57842-27-0
MF:
C7H5BF4S2
Structure:
Chemical Name:
5-IODOCYTOSINE
CAS:
1122-44-7
MF:
C4H4IN3O
Structure:
Chemical Name:
6-AZA-2-THIOTHYMINE
CAS:
615-76-9
MF:
C4H5N3OS
Structure:
Chemical Name:
Thymidine-5'-monophosphate disodium salt
CAS:
33430-62-5
MF:
C10H13N2Na2O8P
Structure:
Chemical Name:
3-METHYLADENINE
CAS:
5142-23-4
MF:
C6H7N5
Structure:
Chemical Name:
2-Amino-6-iodopurine
CAS:
19690-23-4
MF:
C5H4IN5
Structure:
Chemical Name:
RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE
CAS:
6184-17-4
MF:
C17H24N4NaO11P
Structure:
Chemical Name:
1-(2,4,6-Triisopropylphenylsulfonyl)imidazole
CAS:
50257-40-4
MF:
C18H26N2O2S
Structure:
Chemical Name:
Adenine hydrochloride hemihydrate
CAS:
6055-72-7
MF:
C5H8ClN5O
Structure:
Chemical Name:
5-ETHYL-2-THIOURACIL
CAS:
34171-37-4
MF:
C6H8N2OS
Structure:
Chemical Name:
6-Methoxypurine
CAS:
1074-89-1
MF:
C6H6N4O