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5,6-DIHYDROURACIL

Basic information Safety Supplier Related

5,6-DIHYDROURACIL Basic information

Product Name:
5,6-DIHYDROURACIL
Synonyms:
  • TIMTEC-BB SBB007702
  • 2,4(1H,3H)-Pyrimidinedione, dihydro-
  • 3h)-pyrimidinedione,dihydro-4(1h
  • Dihydro-pyrimidine-2,4-dione
  • Hydrouracil
  • 5,6-DIHYDROURACIL
  • 5,6-DIHYDRO-2,4-DIHYDROXYPYRIMIDINE
  • DIHYDRO-2,4(1H,3H)-PYRIMIDINEDIONE
CAS:
504-07-4
MF:
C4H6N2O2
MW:
114.1
EINECS:
207-982-1
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Nucleic acids
Mol File:
504-07-4.mol
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5,6-DIHYDROURACIL Chemical Properties

Melting point:
279-281 °C (lit.)
Boiling point:
213.59°C (rough estimate)
Density 
1.3565 (rough estimate)
refractive index 
1.4487 (estimate)
storage temp. 
2-8°C
solubility 
Soluble in Sodium Hydroxide.
form 
Solid
pka
12.10±0.20(Predicted)
color 
White to Light Beige
BRN 
112496
InChI
InChI=1S/C4H6N2O2/c7-3-1-2-5-4(8)6-3/h1-2H2,(H2,5,6,7,8)
InChIKey
OIVLITBTBDPEFK-UHFFFAOYSA-N
SMILES
C1(=O)NCCC(=O)N1
CAS DataBase Reference
504-07-4(CAS DataBase Reference)
EPA Substance Registry System
2,4(1H,3H)-Pyrimidinedione, dihydro- (504-07-4)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes

MSDS

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5,6-DIHYDROURACIL Usage And Synthesis

Chemical Properties

white to light beige crystalline powder

Uses

Impurity of Uracil.

Uses

5,6-Dihydrouracil acts as an intermediate in the catabolism of uracil.

Uses

Dihydrouracil has been used as a standard for ureido group in the colorimentric assay of transfer ribonucleic acid (tRNA).

Definition

ChEBI: 5,6-dihydrouracil is a pyrimidine obtained by formal addition of hydrogen across the 5,6-position of uracil. It has a role as a metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a uracil.

General Description

Dihydrouracil (DiHU) is a minor base found in transfer ribonucleic acid (tRNA). It is similar to uracil with the only exception that the C5-C6 bond is saturated. It crystallized in the monoclinic system with space group P21/C. Its crystalline structure has been analyzed. Its generation from L-cysteine and uracil via photochemical addition has been described.

5,6-DIHYDROURACIL Preparation Products And Raw materials

Raw materials

5,6-DIHYDROURACILSupplier

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