4-Amino-3-hydrazino-1,2,4-triazol-5-thiol Chemical Properties

Melting point:

228-230 °C (dec.)(lit.)

Boiling point:

275.0±23.0 °C(Predicted)

Density 

2.31±0.1 g/cm3(Predicted)

storage temp. 

0-6°C

solubility 

Soluble in Dimethyl sulfoxide. (DMSO)

pka

8.52±0.20(Predicted)

form 

powder to crystal

color 

White to Almost white

BRN 

134867

Stability:

Light Sensitive

InChIKey

RDIMQHBOTMWMJA-UHFFFAOYSA-N

CAS DataBase Reference

1750-12-5(CAS DataBase Reference)

EPA Substance Registry System

1,2,4-Triazolidin-3-one, 4-amino-5-thioxo-, hydrazone (1750-12-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

1325

WGK Germany 

3

TSCA 

Yes

HazardClass 

4.1

PackingGroup 

III

HS Code 

29339900

MSDS

• Language:English Provider:Purpald
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Amino-3-hydrazino-1,2,4-triazol-5-thiol Usage And Synthesis

Chemical Properties

Beige solid

Uses

A reagent for the determination of aldehydes and other reactive chemicals

Uses

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole is a reagent used in the determination of aldehydes and other reactive chemicals.was used in purpald assay for determination of bacterial polysaccharides containing substituted or unsubstituted glycol in residues such as glycerol, ribitol, arabinitol, furanosyl galactose and sialic acid. It was used as chromogen during the determination of catalase activity in small tissue samples. It was used as reagent in determination of formaldehyde. It was used for derivatization of neutral monosaccharides during HPLC.

Uses

• Purpald^? was used in purpald assay for determination of bacterial polysaccharides containing substituted or unsubstituted glycol in residues such as glycerol, ribitol, arabinitol, furanosyl galactose and sialic acid.
• It was used as chromogen during the determination of catalase activity in small tissue samples.
• It was used as reagent in determination of formaldehyde.
• It was used for derivatization of neutral monosaccharides during HPLC.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 355, 1989 DOI: 10.1002/jhet.5570260216

Purification Methods

Recrystallise Purpald from H2O (0.6g in 300-400mL). The benzylidene derivative has m 245-246o(dec) from i-PrOH [Hoggarth J Chem Soc 4817 1952, Dickinson & Jacobson J Chem Soc, Perkin Trans I 975 1975.[Beilstein 26 III/IV 547.]

4-Amino-3-hydrazino-1,2,4-triazol-5-thiol(1750-12-5)Related Product Information

• Tris(hydroxymethyl)aminomethane
• 1H-Benzotriazole
• 1,2,4-Triazole
• 1,2,3-1H-Triazole
• 6-Aminocaproic acid
• 5-Methyl-1H-benzotriazole
• 1H-1,2,4-Triazole-3-thiol
• Glycine
• 4-Amino-4H-1,2,4-triazole
• ALTRENOGEST
• Malathion
• 3-Amino-5-mercapto-1,2,4-triazole
• Hydrazinium hydroxide solution
• Methylhydrazine
• 4-AMINO-4H-1,2,4-TRIAZOLE-3-THIOL
• AMINO ACIDS
• 4-Amino-3-hydrazino-1,2,4-triazol-5-thiol
• RIBAVIRINA