N4-Benzoylcytosine Chemical Properties

Melting point:

>300 °C (dec.) (lit.)

Density 

1.33±0.1 g/cm3(Predicted)

vapor pressure 

0Pa at 25℃

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Aqueous Acid (Slightly, Heated), DMSO+DCl (Slightly, Heated)

form 

Solid

pka

7.75±0.10(Predicted)

color 

Off-White

InChI

InChI=1S/C11H9N3O2/c15-10(8-4-2-1-3-5-8)13-9-6-7-12-11(16)14-9/h1-7H,(H2,12,13,14,15,16)

InChIKey

XBDUZBHKKUFFRH-UHFFFAOYSA-N

SMILES

C(NC1=CC=NC(=O)N1)(=O)C1=CC=CC=C1

Surface tension

72.2mN/m at 1g/L and 21.2℃

CAS DataBase Reference

26661-13-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29335990

MSDS

• Language:English Provider:SigmaAldrich

N4-Benzoylcytosine Usage And Synthesis

Chemical Properties

White or almost white crystalline powder

Uses

N⁴-Benzoylcytosine may be employed for the following syntheses:

• 3′-C-ethynyl and 3′-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides
• 2′-C-methyl-4′-thiocytidine, via the Pummerer reaction
• 2′-fluorinated L-nucleoside analogs

Uses

N4-Benzoylcytosine is a reactant in the synthesis of 1'',2''-cyclopentyl nucleosides as potential antiviral agents.

General Description

N⁴-Benzoylcytosine is an amide and its anti-microbial activity against pathogenic microorganisms has been studied using the Disk Diffusion and the Pour Plate method. It can be synthesized via the condensation of benzoyl chloride with cytosine.

N4-Benzoylcytosine(26661-13-2)Related Product Information

• Sodium benzoate
• Benzamide
• Cytosine
• Chlorantraniliprole
• Fluorocytosine
• Dihydromyrcenol
• Propanamide, N-(6,7-dihydro-6-oxo-1H-purin-2-yl)-2-methyl-
• N-ALLYLBENZYLAMINE
• N-Allylmethylamine
• 3-Pyridinecarboxamide, 5-chloro-N-methyl-
• 2'-deoxy-2'-fluoro-2'-C-methylcytidine
• 2'-C-Methyl-, 2',3',5'-tribenzoateuridine
• (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-bis(4-chlorobenzoate)
• ((2R,3S,4S)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl)Methyl benzoate
• 3-Pyridinecarboxamide, 4-chloro-N-methyl-
• 4-Pyridinecarboxamide, 3-chloro-N-methyl-
• (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
• 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine