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ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT

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ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT Basic information

Product Name:
ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT
Synonyms:
  • 5'-ADENYLIC ACID SODIUM SALT
  • 5-ADENYLIC ACID, SODIUM SALT
  • 5'-AMP 2NA
  • 5'-AMP DISODIUM SALT
  • 5'-AMP-NA2
  • 5'-AMP SODIUM SALT
  • AMP, 2NA
  • AMP DISODIUM SALT
CAS:
149022-20-8
MF:
C10H17N5NaO8P
MW:
389.24
EINECS:
224-961-2
Product Categories:
  • nucleoside
  • API intermediates
Mol File:
149022-20-8.mol
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ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT Chemical Properties

FEMA 
4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp. 
-20°C
solubility 
H2O: soluble
form 
crystalline
color 
White
CAS DataBase Reference
149022-20-8(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
AU7481600
1-10
HS Code 
29349990

MSDS

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ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT Usage And Synthesis

Uses

Adenosine 5′-monophosphate sodium salt has been used:

  • as a component of reactivation medium to reactivate mouse sperm extracted from caudae epididymides for sperm motility studies
  • as a substrate in signal amplification by reversible exchange (SABRE) method to develop biocompatible SABRE hyperpolarization
  • as a substrate in wheat and Aspergillus niger phytase, assay
  • in luciferase assay to monitor intracellular α-synuclein oligomerization in S1S2 cells
  • to study its effects on induction of therapeutic hypothermia and neuronal damage in a rat model of cardiac arrest (CA) and resuscitation

Definition

ChEBI: Adenosine 5'-phosphate disodium is an organic molecular entity.

Biochem/physiol Actions

Adenosine 5′-monophosphate (5′-AMP) is used to enhance flavor in meat and poultry soups. It is also used as a food additive for specific nutritional purposes. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). Along with inosine monophosphate (IMP), AMP mediates the dissociation of skeletal muscle actomyosin to actin and myosin. Therefore, these two factors may be involved in causing the resolution of rigor mortis in muscles.

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