ChemicalBook > Product Catalog > Biochemical Engineering > Nucleoside drugs > Nucleotides and their analogs > 5-Chlorouracil
5-Chlorouracil
5-Chlorouracil Basic information
- Product Name:
- 5-Chlorouracil
- Synonyms:
-
- TIMTEC-BB SBB004103
- 2,4(1H,3H)-Pyrimidinedione,5-chloro-
- 2,4-Pyrimidinediol,5-chloro-
- 3h)-pyrimidinedione,5-chloro-4(1h
- 5-Chloro-1,2,3,4-tetrahydropyrimidine-2,4-dione
- 5-Chloropyrimidine-2,4-diol
- 5-Chlorouracil,99%
- Fluorouracil Related CoMpound E
- CAS:
- 1820-81-1
- MF:
- C4H3ClN2O2
- MW:
- 146.53
- EINECS:
- 217-339-7
- Product Categories:
-
- Pyrimidine series
- Heterocyclic Compounds
- Biochemistry
- Nucleobases and their analogs
- Nucleosides, Nucleotides & Related Reagents
- Nucleic acids
- PYRIMIDINE
- Pyridines, Pyrimidines, Purines and Pteredines
- Bases & Related Reagents
- Heterocycles
- Nucleotides
- Mol File:
- 1820-81-1.mol
More
Less
5-Chlorouracil Chemical Properties
- Melting point:
- >300 °C (lit.)
- Density
- 1.6838 (rough estimate)
- refractive index
- 1.6550 (estimate)
- storage temp.
- 2-8°C
- solubility
- 1 M NH4OH: soluble50mg/mL
- pka
- 6.77±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 2.501g/L(25 ºC)
- BRN
- 127173
- InChIKey
- ZFTBZKVVGZNMJR-UHFFFAOYSA-N
- CAS DataBase Reference
- 1820-81-1(CAS DataBase Reference)
- EPA Substance Registry System
- 5-Chlorouracil (1820-81-1)
More
Less
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 3
- RTECS
- YQ9410000
- HS Code
- 29335995
MSDS
- Language:English Provider:5-Chlorouracil
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
More
Less
5-Chlorouracil Usage And Synthesis
Chemical Properties
white to light beige crystalline powder
Uses
5-Chlorouracil was used as a control in resazurin-based cytotoxicity assay for screening of cytotoxicity in hepatocytes and liver cell lines.
Uses
5-Chlorouracil can be used for the experimental and clinical treatment of neoplastic and viral diseases.
Definition
ChEBI: An organochlorine compound consisting of uracil having an chloro substituent at the 5-position.
General Description
The shape resonance spectra of 5-chlorouracil, obtained from fixed-nuclei elastic scattering calculations by the Schwinger multichannel method with pseudopotentials, was studied.
Purification Methods
It recrystallises from hot H2O (4g/500mL) using charcoal. [McOmie et al. J Chem Soc 3478 1955, West & Barrett J Am Chem Soc 76 3146 1954, Beilstein 24 III/IV 1231.]
5-ChlorouracilSupplier
Jiangxi ruiya pharmaceutical co., LTD Gold
- Tel
- 19170706235
- hwp@ruiyapharma.com
Jiangsu Zhongyuan Chemicals Co.,Ltd. Gold
- Tel
- 0513-84539538 13817775327
- jinjing860329@163.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
INTATRADE GmbH
- Tel
- +49 3493/605464
- sales@intatrade.de
More
Less
5-Chlorouracil(1820-81-1)Related Product Information
- Uracil
- Difluorochloromethane
- 5-Chlorouridine
- Terbacil
- 5-CHLORO-6-METHYLURACIL
- 4-AMINOPYRAZOLO[3,4-D]PYRIMIDINE
- 6-Chlorouracil
- 6-methyl-5-chlorouracil
- 1,3-Dimethyl-4-chlorouracil,1,3-DIMETHYL-6-CHLOROURACIL
- 3-Methyl-6-chlorouracil, GC 97%,3-METHYL-6-CHLOROURACIL
- 2,4(1H,3H)-Pyrimidinedione,5-chloro-6-(chloromethyl)-(9CI)
- 5-CHLORO-2'-DEOXYURIDINE
- 1-(3-Fluoro-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-chlorouracil
- 5-Chloro-2',3'-O-isopropylidene-D-uridine
- 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidene-D-uridine
- 5-Chlorouracil-15N2,13C
- 1,3,5-TRICHLOROURACIL
- 5-CHLORO-5'-DEOXYURIDINE