ChemicalBook > CAS DataBase List > 5-Chlorouracil

5-Chlorouracil

Product Name
5-Chlorouracil
CAS No.
1820-81-1
Chemical Name
5-Chlorouracil
Synonyms
5-CHLOROPYRIMIDINE-2,4(1H,3H)-DIONE;Fluorouracil EP Impurity E;5-Chloro-1H-pyrimidine-2,4-dione;NSC 28172;5-chloro-uraci;5-CHLOROURACIL;Uracil,5-chloro-;5-CHLORO-5-URACIL;5-Chlorouracil,99%;5-Chlorouracil,98%
CBNumber
CB6216858
Molecular Formula
C4H3ClN2O2
Formula Weight
146.53
MOL File
1820-81-1.mol
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5-Chlorouracil Property

Melting point:
>300 °C (lit.)
Density 
1.6838 (rough estimate)
refractive index 
1.6550 (estimate)
storage temp. 
2-8°C
solubility 
1 M NH4OH: soluble50mg/mL
pka
6.77±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
2.501g/L(25 ºC)
BRN 
127173
InChIKey
ZFTBZKVVGZNMJR-UHFFFAOYSA-N
CAS DataBase Reference
1820-81-1(CAS DataBase Reference)
EPA Substance Registry System
5-Chlorouracil (1820-81-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
YQ9410000
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
224588
Product name
5-Chlorouracil
Purity
99%
Packaging
5g
Price
$92.1
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2867
Product name
Fluorouracil Related Compound E
Purity
certified reference material, pharmaceutical secondary standard
Packaging
50MG
Price
$608
Updated
2024/03/01
Sigma-Aldrich
Product number
1279054
Product name
Fluorouracil Related Compound E
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1210
Updated
2024/03/01
TCI Chemical
Product number
C0969
Product name
5-Chlorouracil
Purity
>98.0%(T)
Packaging
5g
Price
$62
Updated
2024/03/01
TCI Chemical
Product number
C0969
Product name
5-Chlorouracil
Purity
>98.0%(T)
Packaging
25g
Price
$180
Updated
2024/03/01
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5-Chlorouracil Chemical Properties,Usage,Production

Chemical Properties

white to light beige crystalline powder

Uses

5-Chlorouracil was used as a control in resazurin-based cytotoxicity assay for screening of cytotoxicity in hepatocytes and liver cell lines.

Uses

5-Chlorouracil can be used for the experimental and clinical treatment of neoplastic and viral diseases.

Definition

ChEBI: An organochlorine compound consisting of uracil having an chloro substituent at the 5-position.

General Description

The shape resonance spectra of 5-chlorouracil, obtained from fixed-nuclei elastic scattering calculations by the Schwinger multichannel method with pseudopotentials, was studied.

Purification Methods

It recrystallises from hot H2O (4g/500mL) using charcoal. [McOmie et al. J Chem Soc 3478 1955, West & Barrett J Am Chem Soc 76 3146 1954, Beilstein 24 III/IV 1231.]

5-Chlorouracil Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chlorouracil Suppliers

Jiangxi ruiya pharmaceutical co., LTD
Tel
19170706235
Email
hwp@ruiyapharma.com
Country
China
ProdList
80
Advantage
55
Jiangsu Zhongyuan Chemicals Co.,Ltd.
Tel
0513-84539538 13817775327
Email
jinjing860329@163.com
Country
China
ProdList
19
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
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View Lastest Price from 5-Chlorouracil manufacturers

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
5-Chlorouracil 1820-81-1
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2021-05-14
Hebei Mojin Biotechnology Co., Ltd
Product
5-Chlorouracil 1820-81-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-22
Hebei Guanlang Biotechnology Co., Ltd.
Product
5-Chlorouracil 1820-81-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-10-20

1820-81-1, 5-ChlorouracilRelated Search:


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  • C4H3ClN2O2
  • Building Blocks
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  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
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  • Pyridines, Pyrimidines, Purines and Pteredines