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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Nucleoside drugs >  Nucleotides and their analogs >  RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE

RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE

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RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE Basic information

Product Name:
RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE
Synonyms:
  • RIBOFLAVIN 5'-PHOSPHATE SODIUM, DIHYDRATE
  • RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE
  • SODIUM VITAMIN B2 PHOSPHATE DIHYDRATE
  • SODIUM RIBOFLAVINE PHOSPHATE DIHYDRATE
  • FLAVINE MONONUCLEOTIDE NA, DIHYDRATE
  • FLAVINE MONONUCLEOTIDE SODIUM SALT DIHYDRATE
  • FLAVINMONONUCLEOTIDE DIHYDRATE
  • FLAVIN MONONUCLEOTIDE MONOSODIUM SALT DIHYDRATE
CAS:
6184-17-4
MF:
C17H24N4NaO10P
MW:
498.36
EINECS:
204-988-6
Mol File:
6184-17-4.mol
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RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE Chemical Properties

Melting point:
>300°C
storage temp. 
2-8°C
solubility 
H2O: 0.1 g/mL, clear, orange-yellow
form 
powder
color 
Orange to Dark Orange
Water Solubility 
Soluble in water at 50mg/ml
Merck 
14,8201
BRN 
4106529
Stability:
Stable. Incompatible with strong oxidizing agents.
InChI
InChI=1/C17H21N4O9P.Na.H2O.H/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;;;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);;1H2;/t11-,12+,14-;;;/s3
InChIKey
YDUBDYSQHQHEEE-GUYVJCBKNA-N
SMILES
C(N1C2=NC(=O)NC(=O)C2=NC2C=C(C)C(C)=CC1=2)[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O.[NaH].O |&1:19,21,23,r|
CAS DataBase Reference
6184-17-4(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
8
TSCA 
Yes
HS Code 
29362300

MSDS

  • Language:English Provider:ACROS
  • Language:English Provider:ALFA
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RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE Usage And Synthesis

Description

Riboflavin 5''-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways. FMN also binds the FMN riboswitch (RFN element) on RNA to alter gene regulation. FMN is a substrate of FMN phosphohydrolases and is used to study their function.

Chemical Properties

Yellowish crystalline powder

Uses

Riboflavin 5′-monophosphate (FMN) is used as a prosthetic group by oxidoreductase (one and two electron transfer) enzymes such as NADH dehydrogenases, nitric oxide synthases, and nitrilotriacetate monooxygenases. Riboflavin 5′-monophosphate is used as a substrate to study the specificity and kinetics of FMN phosphohydrolases. FMN is used to study molecular sensing based gene regulation by riboswitches.

Uses

Riboflavin 5''-(Dihydrogen Phosphate) Monosodium Salt Dihydrate is a phosphated nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).

General Description

Riboflavin 5′-monophosphate (FMN) is highly soluble in water. Flavins are considered as blue-light absorbing dyes.

Biochem/physiol Actions

Riboflavin 5′-monophosphate (FMN) acts as a cofactor in flavoproteins and possess biological activity in enzymes?and photoreceptors.

Purification Methods

Purify FMN by paper chromatography using tert-butanol/water, cutting out the main spot and eluting it with water. It can also be purified by adsorption onto an apo-flavodoxin column, followed by elution and freeze drying. It crystallises from aqueous acidic solution. [Mayhew & Strating Eur J Biochem 59 539 1976, Beilstein 26 III/IV 2555.]

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