2-Aminopurine Chemical Properties

Melting point:

280-282 °C (lit.)

Boiling point:

238.81°C (rough estimate)

Density 

1.3795 (rough estimate)

refractive index 

1.7000 (estimate)

storage temp. 

2-8°C

solubility 

Aqueous Acid (Slightly), Methanol (Slightly, Heated)

form 

Amorphous Powder

pka

8.02±0.20(Predicted)

color 

Light beige

Stability:

Hygroscopic

InChIKey

MWBWWFOAEOYUST-UHFFFAOYSA-N

CAS DataBase Reference

452-06-2(CAS DataBase Reference)

NIST Chemistry Reference

Purine, 2-amino-(452-06-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38-20/21/22

Safety Statements 

22-36-26

WGK Germany 

3

RTECS 

UO7475000

HS Code 

29349990

Toxicity

mmo-sat 100 mg/PLATE MUREAV 111,283,83

MSDS

• Language:English Provider:9H-Purin-2-amine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2-Aminopurine Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

A probe of structural dynamics and charge transfer in DNA .

Uses

2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes.

Uses

A probe of structural dynamicas and charge transfer in DNA

Definition

ChEBI: The parent compound of the 2-aminopurines, comprising a purine core carrying an amino substituent at the 2-position.

Biochem/physiol Actions

2-Aminopurine (2AP) is an analog of guanosine and adenosine, which can base pair with cytosine and thymine. It is used as a fluorescent probe in nucleic acid structure and dynamics. 2-Aminopurine (2-AP) inhibits double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

2-Aminopurine(452-06-2)Related Product Information

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• EC 2.6.1.2
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• 2-Amino-6-chloropurine-9-riboside
• 6-MERCAPTO-2-AMINOPURINE RIBOSIDE
• 6-CHLORO-2-AMINOPURINE
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• 2,6-DIAMINOPURINE SULPHATE MONOHYDRATE
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• 2-aminopurine-6(1h)-thione,6-mercapto-2-aminopurin
• 2-aminopurine-6,8-diol