EC 2.6.1.2
EC 2.6.1.2 Basic information
- Product Name:
- EC 2.6.1.2
- Synonyms:
-
- L-ALANINE AMINOTRANSFERASE
- L-ALANINE: 2-OXOGLUTARATE AMINOTRANSFERASE
- GPT
- GPT, HUMAN
- GLUTAMIC-PYRUVIC TRANSAMINASE
- GLUTAMATE-PYRUVATE TRANSAMINASE
- GLUTAMATE PYRUVATE TRANSAMINASE, HUMAN
- EC 2.6.1.2
- CAS:
- 9000-86-6
- MF:
- C11H16N2O6
- MW:
- 272.25454
- EINECS:
- 232-561-4
- Product Categories:
-
- Application Index
- Organic Synthesis
- Organic Synthesis and Immobilized Enzymes
- Mol File:
- 9000-86-6.mol
EC 2.6.1.2 Chemical Properties
- storage temp.
- -70°C
- form
- suspension (aqueous)
- color
- green-yellow
- Water Solubility
- Dissolves readily at 5 mg/ml in 0.05M potassium phosphate pH 7.5 to give a clear, pale-green solution. Soluble in distilled water or dilute buffer.
- BRN
- 3562140
- EPA Substance Registry System
- Aminotransferase, alanine (9000-86-6)
Safety Information
- WGK Germany
- 3
- F
- 10
- TSCA
- Yes
MSDS
- Language:English Provider:SigmaAldrich
EC 2.6.1.2 Usage And Synthesis
Uses
It is used for research and clinical diagnostic assays for liver disease. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. Some of the other applications include Diagnostic Controls, calibrators & standards, immunoassays, clinical chemistry, testing/assay validation, life Science, manufacturing, validation Studies.
General Description
Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver.
Biochem/physiol Actions
Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine. It plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported.
EC 2.6.1.2Supplier
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EC 2.6.1.2(9000-86-6)Related Product Information
- COBALT ETHYLENE DIAMINE CHLORIDE
- Tris(2,4-pentanedionato)chroMiuM(III)
- DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
- SALCOMINE
- COBALT(II) ACETYLACETONATE
- Benzyl isocyanide
- Ethyl isocyanoacetate
- TERT-BUTYL ISOCYANIDE
- Cupric acetylacetonate
- PHENYLSELENOL
- Tosylmethyl isocyanide
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
- METHYL ISOCYANOACETATE
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
- Aluminum acetylacetonate
- N-BUTYLISOCYANIDE
- 2,4-PENTANEDIONE, SILVER DERIVATIVE