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Potassium orotate

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Potassium orotate Basic information

Product Name:
Potassium orotate
Synonyms:
  • OROTIC ACID MONOPOTASSIUM SALT
  • OROTIC ACID POTASSIUM SALT
  • POTASSIUM OROTATE
  • 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacimonopotassiumsal
  • 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacimonopotassiumsalt
  • ba2658
  • dioron
  • 6-CARBOXY-2,4-DIHYDROXYPYRIMIDINE MONOPOTASSIUM SALT
CAS:
24598-73-0
MF:
C5H3KN2O4
MW:
194.19
EINECS:
246-341-0
Product Categories:
  • Fine Chemical
Mol File:
24598-73-0.mol
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Potassium orotate Chemical Properties

Melting point:
>300°C
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Aqueous Base (Slightly)
form 
Solid
color 
White to Light Yellow
Stability:
Hygroscopic
LogP
-0.928 (est)
CAS DataBase Reference
24598-73-0(CAS DataBase Reference)
EPA Substance Registry System
4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, monopotassium salt (24598-73-0)
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Safety Information

WGK Germany 
2
RTECS 
RM3201500
HazardClass 
IRRITANT

MSDS

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Potassium orotate Usage And Synthesis

Uses

Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

Potassium orotateSupplier

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