ChemicalBook > Product Catalog > Biochemical Engineering > Nucleoside drugs > Nucleotides and their analogs > 5-METHYLCYTOSINE
5-METHYLCYTOSINE
5-METHYLCYTOSINE Basic information
- Product Name:
- 5-METHYLCYTOSINE
- Synonyms:
-
- 4-Amino-5-methyl-2-pyrimidinol
- Cytosine, 5-methyl-
- 5-Methylcytosine,>96%
- 2(1H)-Pyrimidinone, 4-amino-5-methyl- (9CI)
- 4-amino-5-methyl-3H-pyrimidin-2-one
- 5-METHYLCYTOSINE
- 2(1H)-Pyrimidinone, 6-amino-5-methyl-
- 2(1H)-Oxo-4(3H)-imino-5-methylpyrimidine
- CAS:
- 554-01-8
- MF:
- C5H7N3O
- MW:
- 125.13
- EINECS:
- 209-058-3
- Product Categories:
-
- Nucleic acids
- Pyrimidines
- PYRIMIDINE
- Elisa Kit-Rat Elisa Kit
- Mol File:
- 554-01-8.mol
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5-METHYLCYTOSINE Chemical Properties
- Melting point:
- 270°C (rough estimate)
- Boiling point:
- 232.57°C (rough estimate)
- Density
- 1.2602 (rough estimate)
- refractive index
- 1.6510 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Methanol (Sparingly, Heated)
- pka
- 9.05±0.10(Predicted)
- form
- Crystalline
- color
- White to Off-White
- Water Solubility
- Soluble in water.
- Merck
- 14,6050
- InChI
- InChI=1S/C5H7N3O/c1-3-2-7-5(9)8-4(3)6/h2H,1H3,(H3,6,7,8,9)
- InChIKey
- LRSASMSXMSNRBT-UHFFFAOYSA-N
- SMILES
- C1(=O)NC(N)=C(C)C=N1
- CAS DataBase Reference
- 554-01-8(CAS DataBase Reference)
MSDS
- Language:English Provider:ALFA
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5-METHYLCYTOSINE Usage And Synthesis
Chemical Properties
Crystals in prisms from water.
Uses
5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde.
Definition
ChEBI: A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.
IC 50
Microbial Metabolite; Human Endogenous Metabolite
Purification Methods
Crystallise it from water (solubility is 3.4%). The hydrochloride has m 299-301o (sintering at 280o) (from aqueous HCl/Me2CO). [Hitchings et al. J Biol Chem 177 537 1949, Cohn J Am Chem Soc 73 1539 1951, Beilstein 25 II 183, 25 III/IV 3727.]
5-METHYLCYTOSINESupplier
Tianjin Hexin Chengsai Science and Technology Development Co., Ltd. Gold
- Tel
- 022-23410962 13752273685
- suna@hisyntech.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
Beijing HwrkChemical Technology Co., Ltd
- Tel
- 18515581800 18501085097
- sales.bj@hwrkchemical.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
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5-METHYLCYTOSINE(554-01-8)Related Product Information
- 5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
- 5-(TRIFLUOROMETHYL)-2'-DEOXYCYTIDINE
- 5-CARBOXYCYTOSINE
- 5-METHYLCYTOSINE
- 1-(2-Deoxy-beta-D-ribofuranosyl)-5-methylcytosine
- 2'-C-Methylcytidine
- 2-O-Methylcytosine
- 5-METHYLCYTOSINE HCL,5-METHYLCYTOSINE HYDROCHLORIDE 98%,5-METHYLCYTOSINE HYDROCHLORIDE,5-Methylcytosine hydrochloride ,98%
- 5-HYDROXYMETHYLCYTOSINE
- N4-Methylcytosine ,98%,N4-Methylcytosine
- Cytosine
- 5-Methylcytidine
- FLUORESCEIN-12-DCTP
- BIOTIN-11-DDCTP
- 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE
- 5'-METHYL-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE TRILITHIUM SALT
- N4-BENZOYL-5-METHYLDEOXYCYTIDINE
- 3-METHYLCYTOSINE HYDROCHLORIDE