5-METHYLCYTIDINE
5-METHYLCYTIDINE Basic information
- Product Name:
- 5-METHYLCYTIDINE
- Synonyms:
-
- 5-METHYLCYTIDINE
- 5-METHYLCYTIDINE, 98.0+%(LC)(T)
- Cytidine, 5-Methyl-
- 3: PN: US20060035254 PAGE: 63 claimed sequence
- NSC 363933
- 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidin-2-one
- 4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidin-2(1H)-one
- 5-Me-Cr
- CAS:
- 2140-61-6
- MF:
- C10H15N3O5
- MW:
- 257.24
- EINECS:
- 218-390-8
- Product Categories:
-
- Biochemistry
- Nucleosides and their analogs
- Nucleosides, Nucleotides & Related Reagents
- Biochemicals and Reagents
- Nucleoside Analogs
- Nucleosides, Nucleotides, Oligonucleotides
- Mol File:
- 2140-61-6.mol
5-METHYLCYTIDINE Chemical Properties
- Melting point:
- 212-215 °C (dec.) (lit.)
- Boiling point:
- 537.5±60.0 °C(Predicted)
- Density
- 1.79
- refractive index
- 15 ° (C=2, H2O)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
- pka
- pK1:4.21 (25°C)
- form
- Solid
- color
- Off-White to Pale Beige
- Stability:
- Hygroscopic
- InChIKey
- ZAYHVCMSTBRABG-JXOAFFINSA-N
- CAS DataBase Reference
- 2140-61-6(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- HS Code
- 29389090
MSDS
- Language:English Provider:SigmaAldrich
5-METHYLCYTIDINE Usage And Synthesis
Chemical Properties
White powder
Uses
5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.
Uses
5-Methylcytidine is used in studies of DNA methylation processes (epigenetics).
Definition
ChEBI: 5-methylcytidine is a methylcytidine.
General Description
5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).
Biochem/physiol Actions
5-Methylcytidine is an alkylated pyrimidine plays an important role enhancing the stacking in A- and B- helices of nucleic acid, results in increase of the melting temperature and improves thermal stability leading to structural stabilization.
5-METHYLCYTIDINESupplier
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5-METHYLCYTIDINE(2140-61-6)Related Product Information
- 5-METHYLCYTIDINE
- DMT-2′O-Methyl-rC(ac) Phosphoramidite
- 3-Methylcytidine
- 2''-METHYLCYTIDINE,2'-C-METHYLCYTIDINE
- N4-BENZOYL-5'-O-DMT-CYTIDINE
- 2'-O-METHYLCYTIDINE
- N4-BENZOYL-2'-O-METHYLCYTIDINE
- 2''-DEOXY-5-METHYLCYTIDINE (5-METHYL-2''-DEOXYCYTIDINE),2'-DEOXY-5-METHYLCYTIDINE
- 5'-O-(4,4-Dimethoxytrityl)-N-[[4-(tert-butyl)phenoxy]acetyl]-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
- 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine
- Cytidine
- 5-PROPYNYLCYTIDINE
- BIOTIN-11-CTP
- 5-METHYLCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
- 5-(1-PROPYNYL)-2'-O-METHYLCYTIDINE
- 1-(3,5-DI-O-ACETYL-BETA-D-RIBOFURANOSYL)-4-(1,2,4-TRIAZOL-L-YL)-5-METHYLPYRMIDIN-2-ONE
- N4-(DIISOBUTYLAMINOMETHYLIDENE)-5'-O-(DIMETHOXYTRITYL)-5-(1-PROPYNYL)-2'-O-METHYLCYTIDINE
- 3'-(O-METHYL)-5-METHYLCYTIDINE