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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information

Product Name:
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Synonyms:
  • 8-bromoadenosine-3’,5’-cyclicmonophosphate(8-br-camp),sodiumsalt
  • CAMP, 8-BR, NA
  • ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT
  • 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • 8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT
  • 8-BROMO-CAMP, NA
  • 8-BROMO-CAMP, SODIUM SALT
CAS:
76939-46-3
MF:
C10H12BrN5NaO6P
MW:
432.1
Product Categories:
  • Cyclic Nucleotide related
Mol File:
76939-46-3.mol
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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties

Melting point:
>264°C )dec._
storage temp. 
-20°C
solubility 
H2O: 100 mg/mL
form 
powder
color 
off-white
Water Solubility 
Soluble in water (100mM)
BRN 
7739743
Stability:
Hygroscopic, Moisture Sensitive
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
F 
10-21
HS Code 
29349990

MSDS

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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis

Chemical Properties

Off-white powder

Uses

8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used:

  • to study its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell culture
  • used to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis and morphological changes in the nuclei
  • in superfusion medium for head kidneys stimulation

General Description

8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide.

Biological Activity

Cell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA Tocriset™ .

Biochem/physiol Actions

Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.

storage

-20°C (desiccate)

8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALTSupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Email
product02@bidepharm.com
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Email
info@adooq.cn
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