4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONYL DICHLORIDE Chemical Properties

Melting point:

130-132 °C

Boiling point:

474.2±45.0 °C(Predicted)

Density 

1.834±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Acetone (Slightly), Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)

pka

-5.05±0.16(Predicted)

form 

Solid

color 

Pale Brown to Light Brown

Stability:

Hygroscopic, Moisture Sensitive

CAS DataBase Reference

671-89-6

4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONYL DICHLORIDE Usage And Synthesis

Chemical Properties

Brown Solid

Uses

Chlorothiazide intermediate.

Production Methods

4-Amino-6-chloro-1,3-benzenedisulfonyl Chloride is obtained by chlorosulfonation of 3-chloroaniline with 11 mol of chlorosulfuric acid at 130 ℃; after the chlorosulfonation mixture is treated with 4 mol of thionyl chloride at 80 ℃, the yield is 90 %.

4-AMINO-6-CHLORO-BENZENE-1,3-DISULFONYL DICHLORIDE(671-89-6)Related Product Information

• 5-Chloro Hydrochlorothiazide
• 3-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
• 2,3-DICHLOROBUTANE
• alpha-methylcholine
• (2,4-dichlorophenyl)methyl acetate
• ALLOPURINOL IMPURITY C
• synthesis-015
• Galeterone
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• synthesis-015-HCl
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• HYDROCHLOROTHIAZIDE-3,3-D2
• Hydrochlorothiazide-13C,d2
• Hydrochlorothiazide Impurity 4
• 1-CHLOROPHTHALAZINE
• 5-Chloroorthanilic acid
• Salicylamide