9ALPHA,11,15S-TRIHYDROXY-THROMBA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID
9ALPHA,11,15S-TRIHYDROXY-THROMBA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID Basic information
- Product Name:
- 9ALPHA,11,15S-TRIHYDROXY-THROMBA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID
- Synonyms:
-
- THROMBOXANE B2-D4
- (5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-heptenoic Acid-d4
- (5Z,9α,13E,15S)9,11,15-TrihydroxythroMboxa-5,13-dien-1-oic Acid-d4
- 8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid HeMiacetal-d4
- TXB2-d4
- 9ALPHA,11,15S-TRIHYDROXY-THROMBA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID
- XNRNNGPBEPRNAR-LCGOHBJFSA-N
- CAS:
- 1346112-79-5
- MF:
- C20H30D4O6
- MW:
- 374.51
- Product Categories:
-
- Fatty Acid Derivatives & Lipids
- Glycerols
- Heterocycles
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Pharmaceuticals
- Metabolites & Impurities
- Mol File:
- Mol File
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9ALPHA,11,15S-TRIHYDROXY-THROMBA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: >50 mg/ml (from TXB2),DMSO: >25 mg/ml (from TXB2),Ethanol: >100 mg/ml (from TXB2),PBS pH 7.2: >100 μg/ml (from TXB2)
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9ALPHA,11,15S-TRIHYDROXY-THROMBA-5Z,13E-DIEN-1-OIC-3,3,4,4-D4 ACID Usage And Synthesis
Uses
The labelled analogue of an inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 (D230555) and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.
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