MCOPS6 Chemical Properties

storage temp. 

-20°C

form 

buffered aqueous glycerol solution

biological source

rabbit

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

MCOPS6 Usage And Synthesis

Uses

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biological Activity

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5μ untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq]

IC 50

IL-6; COX-2

Description

Bone Morphogenetic Protein-4 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 116 amino acids and having a molecular mass of 13kDa.
The BMP-4 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

MCOPS6(1629625-47-3)Related Product Information

• Kremen1
• latent GDF-8
• Biotinylated Human Siglec2 / CD22 Protein
• /CD3E (C-6His)
• TRDC
• AAV9 VP2
• CD63
• Recombinant Human Fc γ RIIIb/CD16b(NA1) His Tag
• Caspase 2 (ICH1, Nedd2), Apoptosis Detection, Colorimetric BioAssay&ordf
• CCL13