Lusutrombopag
Lusutrombopag Basic information
- Product Name:
- Lusutrombopag
- Synonyms:
-
- Lusutrombopag S-888711
- (E)-3-[2,6-dichloro-4-[4-[3-[(S)-1-hexyloxyethyl]-2-methoxyphenyl]thiazol-2-ylcarbamoyl]phenyl]-2-methylacrylic acid
- S 888711
- S888711
- S888711;S 888711
- 2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-
- Lusutrombopag,inhibit,Inhibitor,S888711,S 888711,Thrombopoietin Receptor
- Rutroppa
- CAS:
- 1110766-97-6
- MF:
- C29H32Cl2N2O5S
- MW:
- 591.55
- Product Categories:
-
- API
- Mol File:
- 1110766-97-6.mol
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Lusutrombopag Chemical Properties
- Density
- 1.299±0.06 g/cm3(Predicted)
- solubility
- DMSO: 30 mg/ml
- form
- A crystalline solid
- pka
- 4.33±0.21(Predicted)
- color
- White to off-white
- InChIKey
- NOZIJMHMKORZBA-KJCUYJGMSA-N
- SMILES
- C(O)(=O)/C(/C)=C/C1=C(Cl)C=C(C(NC2=NC(C3=CC=CC([C@@H](OCCCCCC)C)=C3OC)=CS2)=O)C=C1Cl
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Lusutrombopag Usage And Synthesis
Uses
Lusutrombopag is a newly discovered thrombopoietin receptor agonist used in the treatment of patients with chronic ITP.
Definition
ChEBI: Lusutrombopag is a member of cinnamic acids.
Mechanism of action
Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels.
LusutrombopagSupplier
Changzhou Nuobailang Biomedical Technology Co., Ltd. Gold
- Tel
- 13861006441
- 780864642@qq.com
Shanghai jerryxing Biomedical Technology Co., Ltd Gold
- Tel
- 17721492509
- 643638326@qq.com
Jiangxi ravel Biotechnology Co.,Ltd Gold
- Tel
- 400-880-2824; 13184580281
- hj@ruiweier.cn
Chengdu D-innovation Pharmaceutical Co.，LTD Gold
- Tel
- 028-85105512 17802830247
- baozuqiang@d-innovation.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com