Basic information Safety Supplier Related

Lesinurad Impurity N

Basic information Safety Supplier Related

Lesinurad Impurity N Basic information

Product Name:
Lesinurad Impurity N
Synonyms:
  • lesinurad Impurity E: 4-Carboxybutyramide lesinurad
  • Lesinurad Impurity N
  • 4-[[5-(carboxymethylsulfanyl)-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]amino]-4-oxobutanoic acid
  • Butanoic acid, 4-[[5-[(carboxymethyl)thio]-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]amino]-4-oxo-
CAS:
1533519-99-1
MF:
C21H20N4O5S
MW:
440.47
Mol File:
1533519-99-1.mol
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Lesinurad Impurity N Chemical Properties

Density 
1.56±0.1 g/cm3(Predicted)
pka
2.97±0.10(Predicted)
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Lesinurad Impurity N Usage And Synthesis

Uses

4-[[5-[(Carboxymethyl)thio]-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]amino]-4-oxo-butanoic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.

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