HEXADIMETHRINE BROMIDE Chemical Properties

storage temp. 

2-8°C

solubility 

H₂O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow

form 

gelatinous solid

Water Solubility 

10mg/ml in Water

Merck 

13,4702

CAS DataBase Reference

28728-55-4

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

RIDADR 

2811

WGK Germany 

3

RTECS 

TQ2655000

F 

3-10

HazardClass 

6.1(b)

PackingGroup 

III

Toxicity

Polymers with mol wt of 5000-10,000 have LD50 i.v. in mice: 25-40 mg/kg (Kimura)

MSDS

• Language:English Provider:SigmaAldrich

HEXADIMETHRINE BROMIDE Usage And Synthesis

Uses

Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant.

Uses

Antiheparin agent. A 3mg quantity has been found to enhance peptide degradation in automated sequential analysis.

Uses

Used as a protein/peptide carrier for protein sequencing.

Definition

ChEBI: Hexadimethrine bromide is a polymer.

General Description

Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA.

storage

Store at +4°C

Purification Methods

Purify it by chromatography on Dowex 50 and/or by filtration through alumina before use [Frank Hoppe-Seyler's Z Physiol Chemie 360 997 1979]. It is hygroscopic, and its solubility in H2O is 10%.

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