ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > Bendamustine Desmethyl Impurity
Bendamustine Desmethyl Impurity
Bendamustine Desmethyl Impurity Basic information
- Product Name:
- Bendamustine Desmethyl Impurity
- Synonyms:
-
- 4-(5-(bis(2-chloroethyl)amino)-1H
- N-desmethyl Bendamustine
- Bendamustine impurity 10/Desmethyl Bendamustine/6-[Bis(2-chloroethyl)amino]-1H-Benzimidazole-2-butanoic Acid
- N-Desmethylbendamustine trifluoroacetate salt
- Bendamustine Impurity 5 (Desmethyl Impurity)
- 1H-Benzimidazole-2-butanoic acid, 6-[bis(2-chloroethyl)amino]-
- Bendamustine M4
- BendamustineImpurity5-d4
- CAS:
- 41515-13-3
- MF:
- C15H19Cl2N3O2
- MW:
- 344.24
- Mol File:
- 41515-13-3.mol
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Bendamustine Desmethyl Impurity Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Acetonitrile:Methanol (1:1): soluble; DMSO: soluble
- form
- A solid
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Bendamustine Desmethyl Impurity Usage And Synthesis
Description
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine (Item No. 23693).1 N-desmethyl Bendamustine is formed through demethylation of the benzimidazole ring in bendamustine by the cytochrome P450 (CYP) isoform CYP1A2. It inhibits proliferation of non-cancerous peripheral blood leukocytes (PBLs; IC50 = 45 µM) and SU-DHL-1, SU-DHL-9, and Daudi lymphoma cells (IC50s = 270, 170, and 120 µM, respectively).WARNING This product is not for human or veterinary use.
Bendamustine Desmethyl ImpuritySupplier
Nanjing XiZe Biotechnology CO., Ltd.
- Tel
- 025-58362220 0086-15250997978
- sale@njxizebio.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shenzhen SUNGENING Bio-Medical Co., Ltd.
- Tel
- 0755-0755-28967200-8062 13631290199
- wxf@sungening.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
TOSUN PHARM
- Tel
- 020-61855200 13326451905
- 260366801@qq.com
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Bendamustine Desmethyl Impurity(41515-13-3)Related Product Information
- Bendamustine Impurity 14
- Bendamustine Impurity 8
- Bendamustine Impurity D
- N1-Methylbenzene-1,2,4-triaMine
- GLUTARIC ACID-2-METHYLAMINO-5-NITROMONOANILIDE
- BendaMustine IMpurity C
- 5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
- 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester
- Bendamustine Impurity 16
- DesMethyl BendaMustine Hydrochloride
- 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
- Bendamustine Impurity 5
- 5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
- Bendamustine Impurity 15
- BendaMustine IMpurity A
- 5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
- Bendamustine Ether Impurity
- 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester