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Choline Fenofibrate Impurity 1

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Choline Fenofibrate Impurity 1 Basic information

Product Name:
Choline Fenofibrate Impurity 1
Synonyms:
  • Choline Fenofibrate Impurity 1
  • Fenofibrate Impurity 1
  • Methanone, (4-chlorophenyl)(2-hydroxyphenyl)-
  • (4-chlorophenyl)(2-hydroxyphenyl)methanone
  • -Chloro-2-hydroxy-benzophenone
  • Pyrotinib Impurity 19
  • Choline Fenofibrate Impurity
CAS:
2985-79-7
MF:
C13H9ClO2
MW:
232.66
Mol File:
2985-79-7.mol
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Choline Fenofibrate Impurity 1 Chemical Properties

Melting point:
77–78°C
Boiling point:
349.3±22.0 °C(Predicted)
Density 
1.307±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly)
form 
Solid
pka
7.63±0.30(Predicted)
color 
Yellow
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Choline Fenofibrate Impurity 1 Usage And Synthesis

Uses

4’-Chloro-2-hydroxy-benzophenone is a useful compound to investigate the effects of substituents on photo-antioxidant abilities of 2-hydroxybenzoyl compounds that can?prevent?autooxidation of plastics under UV light.4’-Chloro-2-hydroxy-benzophenone can also utilized to develop novel?Azomethine Prodrugs of (R)-α-Methylhistamine.

Preparation

Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
? with aluminium chloride without solvent between 120° and 160°, (29%), at 200° for 20 min or in refluxing chlorobenzene for 10 h (53%);
? with trifluoromethanesulfonic acid at 45–55° (6%).

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