ANTI-INFLAMMATORY PEPTIDE 1 Chemical Properties

Boiling point:

1490.7±65.0 °C(Predicted)

Density 

1.270±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

≥107.9 mg/mL in DMSO; insoluble in EtOH; ≥21.13 mg/mL in H2O

pka

2.85±0.10(Predicted)

form 

Lyophilized powder

Sequence

H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

ANTI-INFLAMMATORY PEPTIDE 1 Usage And Synthesis

Uses

Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS). Antiflammin-1 is a derivative of uteroglobin. Antiflammin-1 has anti-inflammatory and antifibrotic actions in bleomycin (HY-108345)-induced lung injury[1][2][3].

in vivo

IC 50

IL-1β

References

[1] Liu W, et al. Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice. Respir Res. 2013 Oct 8;14(1):101. DOI:10.1186/1465-9921-14-101
[2] Camussi G, et al. Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and intradermal inflammatory reactions. J Exp Med. 1990 Mar 1;171(3):913-27. DOI:10.1084/jem.171.3.913
[3] Martínez Leo EE, et al. Biopeptides with antioxidant and anti-inflammatory potential in the prevention and treatment of diabesity disease. Biomed Pharmacother. 2016 Oct;83:816-826. DOI:10.1016/j.biopha.2016.07.051

ANTI-INFLAMMATORY PEPTIDE 1(118850-71-8)Related Product Information

• ANTI-INFLAMMATORY PEPTIDE 3
• Anti-inflammatory peptide2, His-Asp-Met-Asn-Lys-Val-Leu-Asp-Leu,ANTI-INFLAMMATORY PEPTIDE 2
• Anti-inflammatory peptide 204-212
• H-GLY-LEU-GLY-GLY-OH
• H-LEU-BETA-ALA-OH
• AC-VAD-CHO
• H-GLY-ASP-GLY-OH
• ANTI-INFLAMMATORY PEPTIDE 1