CTAP Chemical Properties

storage temp. 

-20°C

form 

Solid

Water Solubility 

Soluble to 1 mg/ml in water

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

CTAP Usage And Synthesis

Uses

CTAP acts as a selective μ-opioid receptor antagonist with a multitude of applications including the regulation of aggressive behavior in mammals. Activation of μ-opioid receptors in the central nucleus of the amygdala, is responsible for mechanisms related to the control of sodium appetite and regulation of sodium intake.

Uses

CTAP has been used as a μ-opioid receptor (MOR) antagonist:

• to study the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitor isoleucine-proline-isoleucine (IPI) and vildagliptin in carrageenan-induced inflammation
• to study the role of MOR in glutamate and gamma-aminobutyric acid (GABA) efflux during predator stress in rats
• to determine the endogenous opioid peptide involved in blocking pain induced by activated gastrin-releasing peptide (Grp⁺) neurons

Biochem/physiol Actions

CTAP is a peptide antagonist produced from somatostatin analogs.

storage

Store at -20°C

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