2,3-DINOR THROMBOXANE B2
2,3-DINOR THROMBOXANE B2 Basic information
- Product Name:
- 2,3-DINOR THROMBOXANE B2
- Synonyms:
-
- 2,3-DINOR-TXB2
- 2,3-DINOR THROMBOXANE B2
- (E)-5-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]pent-3-enoic acid
- (5Z,13E,15S)-9α,11,15-Trihydroxy-2,3-dinorthromboxa-5,13-dien-1-oic acid
- 2,3-dinor Thromboxane B2 Lipid Maps MS Standard
- RJHNVFKNIJQTQF-LMIBIYGPSA-N
- 9ALPHA,11,15S-TRIHYDROXY-2,3-DINOR-THROMBA-5Z,13E-DIEN-1-OIC ACID
- 3-Pentenoic acid, 5-[(2R,3S,4S,6R)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-, (3Z)-
- CAS:
- 63250-09-9
- MF:
- C18H30O6
- MW:
- 342.43
- Mol File:
- 63250-09-9.mol
More
Less
2,3-DINOR THROMBOXANE B2 Chemical Properties
- solubility
- DMF: >50 mg/ml (from TXB2); DMSO: >25 mg/ml (from TXB2); Ethanol: >100 mg/ml (from TXB2); PBS pH 7.2: >100 mg/ml (from TXB2)
More
Less
2,3-DINOR THROMBOXANE B2 Usage And Synthesis
Description
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 2,3-dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker for in vivo TXA2 synthesis. In healthy male volunteers, the median excretion of 2,3-dinor TXB2 is 10.3 ng/hour (138 pg/mg creatine).
Uses
2, 3-Dinor Thromboxane B2-d9 serves as an internal standard for the quantification of 2,3-Dinor TXB2. 2, 3-Dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker in vivo TXA2 synthesis.