N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE Chemical Properties

Boiling point:

77-79 °C/11 mmHg (lit.)

Density 

1.362 g/mL at 20 °C (lit.)

refractive index 

n20/D 1.464

Flash point:

89-90°C/20mm

storage temp. 

2-8°C

solubility 

Miscible with dimethoxyethane.

pka

-6.60±0.70(Predicted)

form 

Oil to Semi-Solid

color 

Colourless to Off-White

Sensitive 

Moisture Sensitive

BRN 

969956

Stability:

Hygroscopic, Moisture Sensitive

CAS DataBase Reference

677-43-0

EPA Substance Registry System

N,N-Dimethyl phosphoramidic dichloride (677-43-0)

Safety Information

Hazard Codes 

C

Risk Statements 

34-37

Safety Statements 

26-36/37/39

RIDADR 

UN 3265 8/PG 3

WGK Germany 

3

RTECS 

TB4025000

F 

1-3-10

HazardClass 

8

PackingGroup 

II

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE Usage And Synthesis

Chemical Properties

Light yellow liquid

Uses

N,N-Dimethylphosphoramidodichloridate is used in the synthesis of phosphoramidates as well as (RS)-ethyl N,N-dimethylphosphoramidocyanidate (Nerve agent GA) which is used as a chemical weapon. It forms active intermediates, which react with alcohols in situ to give esters. It is also used to convert primary alcohols to alkyl chlorides. Furthe, it serves as an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. In addition to this, it reacts with 1,2 diols to prepare cyclic phosphoric amides followed by alkenes after reduction.

N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE(677-43-0)Related Product Information

• N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE (DIMETHYLAMINOPHOSPHORYL DICHLORIDE; N,N-DIMETHYLPHOSPHORAMIC DICHLORIDE; DMPADC
• N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE (DIMETHYLAMINOPHOSPHORYL DICHLORIDE; N,N-DIMETHY
• DI-CHLORO N,N-DIISOPROPYLPHOSPHORAMIDITE
• DIMETHYLPHOSPHORAMIDOUS DICHLORIDE
• AURORA KA-1672
• DICHLORO N,N-DIETHYLPHOSPHORAMIDITE
• N,N-DIMETHYLPHOSPHORAMIDODICHLORIDATE