ANTI-KCA2.2(SK2)
ANTI-KCA2.2(SK2) Basic information
- Product Name:
- ANTI-KCA2.2(SK2)
- Synonyms:
-
- ANTI-POTASSIUM CHANNEL, SK2
- ANTI-POTASSIUM CHANNEL SK2 (APAMIN-SENSITIVE CONDUCTANCE CA2+-DEPENDENT K+ CHANNEL, KCA2, KCNN2, SKCA2)
- ANTI-KCA2.2(SK2)
- Anti-Potassium Channel SK2 (Apamin-Sensitive Conductance Ca2+-Dependent K+ Channel, KCa2, Kcnn2, SKCa2) antibody produced in rabbit
- Anti-HSK2
- Anti-KCa2.2
- Anti-KCNN2 antibody produced in rabbit
- Anti-Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
- MW:
- 0
- Product Categories:
-
- Alphabetical Index
- Antibodies to Ion Channels
- Antibodies to Potassium ChannelsAntibodies
- Antibodies to Voltage-Gated Ion Channels
- PO to PY
- Mol File:
- Mol File
ANTI-KCA2.2(SK2) Chemical Properties
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- rabbit
MSDS
- Language:English Provider:SigmaAldrich
ANTI-KCA2.2(SK2) Usage And Synthesis
Uses
Rabbit Anti-KCNN2 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.
Biological Activity
KCNN2 is an integral membrane protein th at forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This protein is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for KCNN2.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) th at may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN2 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) th at may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein th at forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.