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2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile

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2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile Basic information

Product Name:
2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile
Synonyms:
  • 2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile
  • Crisaborole o-Isomer
  • Benzonitrile, 2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
  • Crisaborole Impurity 24
  • Crisaborole-011
CAS:
906673-30-1
MF:
C14H10BNO3
MW:
251.05
Mol File:
906673-30-1.mol
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2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile Chemical Properties

Boiling point:
414.9±55.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
6.99±0.20(Predicted)
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2-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile Usage And Synthesis

Uses

4-Descyano-2-cyano-Crisaborole was used to prepare a novel benzoxaborole anti-inflmmatory agent for the potential topical treatment of psoriasis and atopic dermatitis.

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