19(R)-HYDROXY PROSTAGLANDIN F1ALPHA Chemical Properties

Boiling point:

594.2±50.0 °C(Predicted)

Density 

1.195±0.06 g/cm3(Predicted)

solubility 

DMF: >50 mg/ml (from PGF1a); DMSO: >50 mg/ml (from PGF1a); Ethanol: >75 mg/ml (from PGF1a); PBS pH 7.2: >2 mg/ml (from PGF1a)

pka

4.78±0.10(Predicted)

19(R)-HYDROXY PROSTAGLANDIN F1ALPHA Usage And Synthesis

Description

19(R)-hydroxy PGF_1α is an ω-1 hydroxylase metabolite of PGF_1α that has been identified in the semen of humans and marsupials.^1,2 There are no published reports on its biological activity.

Definition

ChEBI: 19R-Hydroxy-PGF1alpha is a prostanoid.

References

1. Taylor, P.L., and Kelly, R.W. The occurrence of 19-hydroxy F prostaglandins in human semen FEBS Lett. 57(1),22-25(1975).
2. Marley, P.B., Rodger, J.C., White, I.G., et al. 19-Hydroxylated prostaglandins in the semen of the marsupial Trichosurus vulpecula (brush-tailed possum) Comp. Biochem. Physiol. B Biochem. Mol. Biol. 70(3),619-621(1981).

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