FLUORESCEIN-5-THIOSEMICARBAZIDE Chemical Properties

Boiling point:

723.8±70.0 °C(Predicted)

Density 

1.70±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMF: soluble

pka

9.33 ± 0.20, most acidic, temperature: 25 °C; 1.76 ± 0.19, most basic(at 25℃)

form 

Solid

color 

Yellow solid

Appearance

Solid Powder

λmax

492 nm (Buffer pH 9.0)

Biological Applications

Analyzing low-molecular mass aldehydes in urine, drinking waters; assaying glycosaminoglycan-degrading enzyme activity; detecting sterols; measuring/quantifying degree of hair damage

Major Application

Characterizing soft material interfaces; understanding fibrous network structures; in nanodevice preparation; functionalizing/ encapsulatiing particles by initiated chemical vapor deposition (iCVD); functional polymer coatings; high refractive index coatings; papers

InChI

InChI=1S/C21H15N3O5S/c22-24-20(30)23-10-1-4-14-13(7-10)19(27)29-21(14)15-5-2-11(25)8-17(15)28-18-9-12(26)3-6-16(18)21/h1-9,25-26H,22H2,(H2,23,24,30)

InChIKey

OIMMDIXLTJAVTF-UHFFFAOYSA-N

SMILES

N(C(NC1C=CC2C3(C4=C(C=C(O)C=C4)OC4=C3C=CC(O)=C4)OC(=O)C=2C=1)=S)N

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

8

MSDS

• Language:English Provider:SigmaAldrich

FLUORESCEIN-5-THIOSEMICARBAZIDE Usage And Synthesis

Description

Fluorescein-5-thiosemicarbazide (FTSC) is a fluorescent probe for labeling aldehydes and ketones in cell surface.

Uses

Labeling of cell-surface functional groups (glycophorins). Detection of protein carbonyls in aging tissues.

Uses

Fluorescein-5-thiosemicarbazide can be used for Sox2 transcription factor binds RNA.

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