L-ASPARTIC ACID (3-13C)
L-ASPARTIC ACID (3-13C) Basic information
- Product Name:
- L-ASPARTIC ACID (3-13C)
- Synonyms:
-
- L-ASPARTIC ACID (3-13C)
L -Aspartic acid-3-13C
- CAS:
- 68261-19-8
- MF:
- C4H7NO4
- MW:
- 134.11
- Product Categories:
-
- Amino Acids 13C, 2H, 15N
- Alphabetical Listings
- Amino Acids
- AStable Isotopes
- Stable Isotopes
- Mol File:
- Mol File
L-ASPARTIC ACID (3-13C) Chemical Properties
- Melting point:
- >300 °C (dec.)(lit.)
- optical activity
- [α]25/D +25.0°, c =2 in 5 M HCl
- CAS Number Unlabeled
- 56-84-8
Safety Information
- Safety Statements
- 22-24/25
MSDS
- Language:English Provider:SigmaAldrich
L-ASPARTIC ACID (3-13C) Usage And Synthesis
Uses
L-Aspartic acid-13C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[2][3].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. DOI:10.1046/j.1471-4159.1999.0731206.x
[3] Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug23(4):397-406. DOI:10.1007/BF02353640