2H-1,2,4-Triazole-3-carboxamide Chemical Properties

Melting point:

315 °C

Boiling point:

393.4±25.0 °C(Predicted)

Density 

1.537±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Aqueous Base (Slightly), DMSO (Slightly)

form 

Solid

pka

8.50±0.20(Predicted)

color 

White to Off-White

CAS DataBase Reference

3641-08-5(CAS DataBase Reference)

Safety Information

HS Code 

2933999552

2H-1,2,4-Triazole-3-carboxamide Usage And Synthesis

Uses

N-Des-1-β-D-ribofuranosyl Ribavirin (Ribavirin EP Impurity D) is an impurity in the synthesis of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.

Definition

ChEBI: 1,2,4-triazole-3-carboxamide is a member of the class of triazoles that is 1H-1,2,4-triazole substituted by an aminocarbonyl group at position 3. It is the major catabolite and aglycon of ribavirin. It has a role as a human urinary metabolite and a drug metabolite. It is a member of triazoles, a primary carboxamide, a monocarboxylic acid amide and an aromatic amide.

2H-1,2,4-Triazole-3-carboxamide(3641-08-5)Related Product Information

• N-TERT-BUTYL-3-ISOPROPYL-5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOLE-1-CARBOXAMIDE
• 5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
• N-TERT-BUTYL-3-(2-HYDROXYPROPAN-2-YL)-5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOLE-1-CARBOXAMIDE
• 5-METHYL-2-PHENYL-2H-1,2,3-TRIAZOLE-4-CARBOXAMIDE,5-METHYL-2-PHENYL-2H-1,2,3-TRIAZOLE-4-CARBOXAMIDE
• Rufinamide
• Ribavirin
• TARIBAVIRIN
• 1H-1,2,4-Triazole-3-carboxamide
• N-(2,4-DICHLOROPHENYL)-1-(2,4-DIFLUOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• N-(3,4-DIFLUOROPHENYL)-5-METHYL-1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• 5-METHYL-N,1-BIS[3-(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE,5-METHYL-N,1-BIS[3-(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• 1-(2,4-DIFLUOROPHENYL)-5-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• N,1-BIS(4-CHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE,N,1-BIS(4-CHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• N,1-BIS(2,4-DIFLUOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE,N,1-BIS(2,4-DIFLUOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• 1-(2,4-DIFLUOROPHENYL)-N-(4-FLUOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• 1-(4-CHLOROPHENYL)-5-METHYL-N-(4-METHYLPHENYL)-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• 1-(4-CHLOROPHENYL)-N-(4-METHOXYPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
• 1-(2,4-DIFLUOROPHENYL)-N-ISOPROPYL-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE