Adrenosterone Chemical Properties

Melting point:

219-222 °C(lit.)

alpha 

300 º (c=1 in chloroform)

Boiling point:

381.62°C (rough estimate)

Density 

1.1381 (rough estimate)

refractive index 

290 ° (C=0.2, EtOH)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Solid

color 

White to Off-White

optical activity

[α]20/D +300°, c = 1 in chloroform

Water Solubility 

98.49mg/L(23.5 ºC)

Merck 

14,176

InChIKey

RZRPTBIGEANTGU-IRIMSJTPSA-N

CAS DataBase Reference

382-45-6(CAS DataBase Reference)

NIST Chemistry Reference

Androst-4-ene-3,11,17-trione(382-45-6)

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

Adrenosterone Usage And Synthesis

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Androstenedione is a steroid hormone. It is used to make medicine. Androstenedione is used to increase the production of the hormone testosterone to enhance athletic performance, increase energy, keep red blood cells healthy, enhance recovery and growth from exercise, and increase sexual desire and performance.

Definition

ChEBI: Adrenosterone is a 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17. It has a role as an androgen, a human urinary metabolite, a marine metabolite and an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor. It is a 3-oxo-Delta(4) steroid, a 17-oxo steroid, an androstanoid and an 11-oxo steroid. It derives from a hydride of an androstane.

benefits

Adrenosterone is sold as a dietary supplement since 2007 as a fat loss and muscle gaining supplement. It is thought to be a competitive selective 11βHSD1 inhibitor, which is responsible for activation of cortisol from cortisone. Thus preventing muscle breakdown, and contributing to a majority of its effects.

Purification Methods

Dissolve adrenosterone i n Me2CO, decolorise it with charcoal, filter, add H2O, Me2CO evaporate and the solid is recrystallised from aqueous EtOH. Also recrystallise it from Et2O or Et2O/pentane and dry it at 110o/0.1mm for 2hours. It can be sublimed under high vacuum. [Reichstein Helv Chim Acta 20 953, 979 1937, Mason et al. J Biol Chem 116 267 1936, Beilstein 7 III 4601.]

Adrenosterone(382-45-6)Related Product Information

• Dehydroepiandrosterone
• Quinocetone
• Androsterone
• Epiandrosterone
• 6-Methyl-5-hepten-2-one
• Gestrinone
• Zearalenone
• Androstenedione
• Clethodim
• Ecdysone
• CORTISONE
• Metandienone
• TERT-BUTYLCYCLOHEXANE
• CIS-4-HEPTENAL
• TRANS-2-HEXENAL
• 8-PENTADECANONE
• 1,1,4-TRIMETHYLCYCLOHEXANE
• 2-HEXADECANONE