PENTAETHYLENEHEXAMINE Chemical Properties

Melting point:

-35 °C

Boiling point:

380 °C

Density 

0.95 g/mL at 25 °C (lit.)

vapor pressure 

<1 hPa (20 °C)

refractive index 

n20/D 1.5096(lit.)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

water: soluble500g/L at 20°C

form 

Liquid

pka

10.07±0.19(Predicted)

color 

Clear yellow

PH

11 (10g/l, H2O)

BRN 

1768042

Stability:

Stable. Incompatible with strong oxidizing agents, strong acids.

CAS DataBase Reference

4067-16-7(CAS DataBase Reference)

EPA Substance Registry System

Pentaethylenehexamine (4067-16-7)

Safety Information

Hazard Codes 

C,N

Risk Statements 

34-43-50/53-21/22

Safety Statements 

26-36/37/39-45-60-61

RIDADR 

UN 2735 8/PG 3

WGK Germany 

2

RTECS 

RZ2680000

Autoignition Temperature

360 °C

HazardClass 

8

PackingGroup 

III

HS Code 

29211999

Toxicity

LD50 orl-rat: 1600 mg/kg 37ASAA 7,580,79

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

PENTAETHYLENEHEXAMINE Usage And Synthesis

Chemical Properties

dark yellow-green liquid

Uses

5.Pentaethylenehexamine has been used in the preparation of:

• polyisobutylene succinimide (PIBSI) dispersants, used as engine oil-additives
• poly(glycidyl methacrylate) (P(GMA)) homopolymers
• poly(amidoamine)s

General Description

Yellowish liquid with an odor of ammonia.

Air & Water Reactions

Water soluble.

Reactivity Profile

PENTAETHYLENEHEXAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Contact with eyes can cause slight to moderate irritation and possible burns. May cause transient fogging of the eyes as a result of corneal edema, which is reversible. May cause moderate skin irritation or allergic skin reaction with symptoms of redness, itching, swelling, or rash. Vapors may irritate the eyes, nose, throat, and respiratory tract. May cause coughing, headache, nausea and vomiting. If swallowed, may cause nausea, vomiting and abdominal pain. May cause burns of the mouth, throat, esophagus, and stomach.

Safety Profile

Moderately toxic by ingestion. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

Purification Methods

Fractionally distil it twice at 10-20mm, the fraction boiling at 220-250o being collected. It can be further purified via the hydrochloride. Its solution in MeOH (40mL of base in 250mL) is cooled in an ice-bath and conc HCl (~50mL) is added dropwise with stirring. The precipitated hydrochloride is filtered off, washed with Me2CO, and Et2O, then dried in a vacuum desiccator. The free base is then obtained by basification, extraction into Et2O, drying (NaOH), filtering, evaporating and distilling the residue as before. It forms a Cu complex [Cu(C10H28N6)]2+. [Jonassen et al. J Am Chem Soc 79 4279 1957, Beilstein 4 IV 1245.]

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