3-acetamidophthalic acid Chemical Properties

Melting point:

260 °C

Boiling point:

518.2±45.0 °C(Predicted)

Density 

1.512±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator, under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

2.54±0.10(Predicted)

color 

Pale Yellow

EPA Substance Registry System

3-(Acetylamino)phthalic acid (15371-06-9)

3-acetamidophthalic acid Usage And Synthesis

Uses

3-Acetamidophthalic Acid is an impurity of Apremilast (A729700); an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis. Apremilast EP Impurity B

3-acetamidophthalic acid(15371-06-9)Related Product Information

• 1,2-Benzenedicarboxylicacid,3-(hydroxyamino)-(9CI)
• 1-(3,4-Dimethoxyphenyl)-2-(methylsulfonyl)ethan-1-amine
• 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
• Apremilast Impurity FA
• HHUBRUYPYDODRB-UHFFFAOYSA-N
• Apremilast Impurity G
• Apremilast
• 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone
• 3-Ethoxy-4-methoxybenzaldehyde oxime
• (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
• (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
• Apremilast
• Apremilast
• 3-ETHOXY-4-METHOXYBENZOIC ACID
• Apremilast
• (E)-3-hydroxy-4-methoxybenzaldehyde oxime
• Apremilast Impurity E
• (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt