Frentizole
Frentizole Basic information
- Product Name:
- Frentizole
- Synonyms:
-
- Frentizole
- Frenazole
- N-[6-Methoxybenzo[d]thiazol-2-yl]-N'-phenylurea
- 1-(6-Methoxybenzothiazol-2-yl)-3-phenylurea
- Lilly-53616
- Urea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-
- 1-(6-Methoxybenzo[d]thiazol-2-yl)-3-phenylurea
- β-amyloid peptide,systemic lupus erythematosus,Aβ-ABAD,Inhibitor,rheumatoid arthritis,inhibit,Abeta,immunosuppressant,Amyloid-β,Frentizole
- CAS:
- 26130-02-9
- MF:
- C15H13N3O2S
- MW:
- 299.35
- Mol File:
- 26130-02-9.mol
More
Less
Frentizole Chemical Properties
- Density
- 1.420±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 3 mg/mL (10.02 mM)
- pka
- 7.02±0.70(Predicted)
- form
- Powder
- color
- White to off-white
More
Less
Frentizole Usage And Synthesis
Uses
Immunoregulator.
in vivo
Frentizole (8.2 or 79.9 mg/kg/day for young mice in animal feedings, 52 weeks) can extend the life span of NZB/NZW mice[2].
| Animal Model: | NZB/NZW mice[2] |
| Dosage: | 8.2 or 79.9 mg/kg/day for young mice |
| Administration: | In animal feedings; 52 weeks |
| Result: | Showed that the average lifespan of young untreated mice was 38 weeks, in the low dose group the average lifespan was about 38 weeks, and in the high dose group the lifespan was significantly longer with an average lifespan of about 61 weeks. Significantly suppressed leukocyte counts, compared to a mean peripheral blood leukocyte count of 4160 in control mice, 3217 in low dose treated mice and 3450 in high dose treated mice. Significant increased in terminal neutrophil counts in young low and high dose treated mice compared to control. |
FrentizoleSupplier
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel
- 400-6206333 13167063860
- anhua.mao@aladdin-e.com
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
LETOPHARM LIMITED
- Tel
- +86-21-5821 5861
- sales@letopharm.com
Codow Chemical Co.,Ltd.
- Tel
- 18620099427
- amy@howeipharm.com